Die verbesserten Therapien ermöglichen vielen HIV-Infizierten heute ein weitgehend normales Leben. Dazu gehört für viele auch die Gründung einer Familie, zumal die Risiken einer Mutter-Kind-Übertragung mittlerweile sehr gering sind. Bei der Entscheidung über den Geburtsmodus geht es um die Frage: Ist eine vaginale Entbindung vertretbar?
This is a preview of subscription content, log in via an institution to check access.
Literatur
Warszawski et al,Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal Cohort, AIDS 2008; 22:289–299
European Group CS. Children born to women with HIV-1 infection: natural history and risk of vertical transmission. Lancet 1991; 337:253–260.
Dabis F, Msellati P, Dunn D, Lepage P, Newell ML, Peckham C, Van de Perre P. Estimating the rate of mother-to-child transmission of HIV. Report of a workshop on methodological issues Ghent (Belgium), 17-20 February 1992. The Working Group on Mother-to-Child Transmission of HIV. AIDS 1993; 7:1139–1148.
Connor EM, Sperling RS, Gelber R, Kiselev P, Scott G, O'sullivan MJ, VanDyke R, Bey M, Shearer W, Jacobson RL, et al (1994) Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med 331:1173–80.
European Mode of Delivery Collaboration. Elective caesarean-section versus vaginal delivery in prevention of vertical HIV-1 transmission: a randomised clinical trial. Lancet. 1999 Mar 27;353(9158):1035–9.
The mode of delivery and the risk of vertical transmission of human immunodeficiency virus type 1—a meta-analysis of 15 prospective cohort studies. The International Perinatal HIV Group. N Engl J Med 1999;340:977-987
Gingelmaier A, Hollwitz B, Casteleyn S, Faul-Burbes C, Gröger S, Beichert M, Buchholz B, Weigel M, Funke AM, Grubert TA, Friese K. Schwangerschaftsverlauf und kindliches Outcome bei 599 HIV-exponierten Schwangerschaften an deutschen Schwerpunktzentren 1999–2003. Geburtsh Frauenheilk 2005; 65:1058–1063.
Cooper ER, Charurat M, Mofenson L, et al.; Women and Infants Transmission Study Group. Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. JAIDS 2002; 29:484–494.
Warszawski et al, Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal Cohort, AIDS 2008; 22:289–299
Buchholz B, Beichert M, Marcus U, Grubert T, Gingelmaier A, Haberl A, Schmied B, Brockmeyer NH. German-Austrian recommendations for HIV-therapy in pregnancy and in HIV-exposed newborn, update 2008. Eur J Med Res 2009; 14(11):461–479
Liu S, Liston RM, Joseph KS, Heaman M, Sauve R, Kramer MS; Maternal Health Study Group of the Canadian Perinatal Surveillance System. Maternal mortality and severe morbidity associated with low-risk planned cesarean delivery versus planned vaginal delivery at term. CMAJ. 2007 Feb 13;176(4):455–60.
Marcollet et al, Differences in postpartum morbidity in women who are infected with the human immunodeficiency virus after elective caesarean delivery, emergency caesarea delivery, or vaginal delivery. Am J Obstet Gynecol 2002; 186:784–789
Tubiana R, Le Chenadec J, Rouzioux C et al. Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load <500 copies/ml at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1). Clin Infect Dis. 2010; 50(4):585–96.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gingelmaier, A., Kästner, R., Bolten, M. et al. Wie sollte sie entbinden?. MMW - Fortschritte der Medizin 154, 20–25 (2012). https://doi.org/10.1007/s15006-012-0621-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s15006-012-0621-2