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Applied Biological Chemistry

, Volume 61, Issue 2, pp 163–171 | Cite as

Food, cosmetic and biological applications of characterized DOPA-melanin from Vibrio alginolyticus strain BTKKS3

  • Noble K. Kurian
  • Sarita G. Bhat
Article

Abstract

Melanins are one of the most common pigments produced in nature and distributed throughout the biological kingdom. Vibrio alginolyticus strain BTKKS3 produced DOPA-melanin was used in the study. BTKKS3 melanin inhibited biofilm formation by pathogenic bacteria and effectively decreased the activity of four inflammatory enzymes tested viz. cyclooxygenase, lipoxygenase, myeloperoxidase and nitric oxide synthase. Melanin proved to be less cytotoxic to mouse fibroblast cells with an IC50 value of 134.98 μg/mL. The sun protection factor value of commercial sunscreens was enhanced by 3.42 units by DOPA-melanin.

Keywords

Vibrio alginolyticus Anti-biofilm Anti-inflammatory Sun protection factor 

Supplementary material

13765_2018_343_MOESM1_ESM.docx (35 kb)
Supplementary material 1 (DOCX 34 kb)

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Copyright information

© The Korean Society for Applied Biological Chemistry 2018

Authors and Affiliations

  1. 1.Department of BiotechnologyCochin University of Science and TechnologyKalamassery, CochinIndia

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