Applied Biological Chemistry

, Volume 61, Issue 1, pp 107–111 | Cite as

Changes in postpartum metabolites and resumption of ovarian cyclicity in primiparous and multiparous dairy cows

  • Muhammad Najmus Saqib
  • Muhammad Subhan Qureshi
  • Rifat Ullah Khan
Article
  • 46 Downloads

Abstract

The postpartum period in high-yielding dairy cows creates an enormous drain of nutrients in favor of milk yield which antagonizes the resumption of ovulatory cycles. Therefore, a study was undertaken to evaluate the association of changes in postpartum serum metabolites with resumption of ovarian cyclicity. A total of 24 clinically healthy, freshly parturated primiparous (P-1) and multiparous (P-2) Holstein Frisian cows was selected. Cows were further divided on the basis of body condition score (BCS) 1 and 2 having BCS 3 or above 3, respectively. Weekly blood samples were collected and serum glucose, cholesterol, triglycerides, progesterone, and cortisol concentrations were determined for a period of 7 weeks. The glucose concentration was significantly (P < 0.05) higher in cows in P-2 during week 7. Cows in parity 2 had significantly (P < 0.05) high cholesterol during week 6 and 7. The serum triglyceride concentration in multiparous animals having BCS-2 during week 6 was increased significantly (P < 0.05). Serum cortisol was significantly (P < 0.05) high in P-1 during week 1 and 2 and significantly (P < 0.05) high in P-2 during week 7. Serum progesterone was significantly (P < 0.05) higher in cows during week 7 in P-2 having BCS-2. The increased serum progesterone concentration during postpartum period was associated with decreased levels of serum cortisol and more availability of cholesterol and glucose. The multiparous cows maintained the postpartum blood metabolite concentration and showed better adaptability to reproductive cyclicity during the postpartum period as compared to primiparous cows.

Keywords

Postpartum Metabolism Multiparous Primiparous Cows 

Notes

Acknowledgment

The authors are thankful to the Higher Education Commission (HEC) of Pakistan for funding this work through indigenous Ph.D. scholarship.

References

  1. 1.
    Block SS, Butler WR, Ehrhardt RA, Bell AW, Van Amburgh ME, Boisclair YR (2001) Decreased concentration of plasma leptin in periparturient dairy cows is caused by negative energy balance. J Endocrinol 171:339–348CrossRefGoogle Scholar
  2. 2.
    Royal M, Mann GE, Flint PE (2000) Strategies for reversing the trend towards sub fertility in dairy cattle. Vet J 160:53–60CrossRefGoogle Scholar
  3. 3.
    Butler WR (2003) Energy balance relationships with follicular development, ovulation and fertility in post-partum dairy cows. Livest Prod Sci 83:211–218CrossRefGoogle Scholar
  4. 4.
    Jeong JK, Choi IS, Kang HG, Hur TY, Jung YH, Kim IH (2015) Relationship between serum metabolites, body condition, peri- and post-partum health and resumption of post-partum cyclicity in dairy cows. Livest Sci 181:31–37CrossRefGoogle Scholar
  5. 5.
    Taylor VJ, Beever DE, Bryant MJ, Wathes DC (2003) Metabolic profiles and progesterone cycles in first lactation dairy cows. Theriogenology 59:1661–1677CrossRefGoogle Scholar
  6. 6.
    Mojtaba CR, Thatcher WW, Clark JH (2012) Relation between ovarian activity and energy status during the early post-partum period of high producing dairy cows. J Dairy Sci 73:938–947Google Scholar
  7. 7.
    Shin E, Jeong J, Choi I, Kang H, Hur T, Jung Y, Kim I (2015) Relationships among ketosis, serum metabolites, body condition, and reproductive outcomes in dairy cows. Theriogenology 84:252–260CrossRefGoogle Scholar
  8. 8.
    Opsomer G, Gröhn YT, Hertl J, Coryn M, Deluyker H, de Kruif A (2000) Risk factors for post partum ovarian dysfunction in high producing dairy cows in Belgium: a field study. Theriogenology 53:841–857CrossRefGoogle Scholar
  9. 9.
    Shrestha HK, Nakao T, Suzuki T, Akita M, Higaki T (2005) Relationships between body condition score, body weight, and some nutritional parameters in plasma and resumption of ovarian cyclicity post-partum during pre-service period in high-producing dairy cows in a subtropical region in Japan. Theriogenology 64:855–866CrossRefGoogle Scholar
  10. 10.
    Thatcher WW, Wilcox CJ (2004) Post-partum estrus as an indicator of reproductive status in the dairy cow. J Dairy Sci 56:608–612CrossRefGoogle Scholar
  11. 11.
    Looper ML, Lents CA, Wettemann RP (2003) Body condition at parturition and post-partum weight changes do not influence the incidence of short lived corpora lutea. In post-partum dairy cows. J Dairy Sci 81:2390Google Scholar
  12. 12.
    Carlos AR (2004) Managing the post-partum cow to maximize pregnancy rates, 10 proceedings Florida Dairy Reproduction cycles In first lactation dairy cows. Theriogenology 59:1661–1677Google Scholar
  13. 13.
    El-Azab MA, Badr A, El-Sadawy G, Shawki Borkat TM (1993) Some biochemical changes in relation to post-partum ovarian activity in dairy cows. Indian J Anim Sci 63:1244–1247Google Scholar
  14. 14.
    Balakrishnan V, Balagopal R (1994) Serum calcium, phosphorous, magnesium, copper and zinc levels in regular breeding buffaloes. Indian Vet J 71:23–25Google Scholar
  15. 15.
    Theera R (2010) A field study on negative energy balance in periparturient dairy cows kept in small-holder farms: effect on milk production and reproduction. Thai J Agric Res 5:3157–3163Google Scholar
  16. 16.
    Chalmeh A, Hajimohammadi A, Nazifi S (2015) Endocrine and metabolic responses of high producing Holstein dairy cows to glucose tolerance test based on the stage of lactation. Livest Sci 181:179–186CrossRefGoogle Scholar
  17. 17.
    Shrestha HK, Nakao T, Higaki T, Suzuki T, Akita M (2004) Resumption of post-partum ovarian cyclicity in high-producing Holstein cows. Theriogenology 61:637–649CrossRefGoogle Scholar

Copyright information

© The Korean Society for Applied Biological Chemistry 2018

Authors and Affiliations

  • Muhammad Najmus Saqib
    • 1
  • Muhammad Subhan Qureshi
    • 1
  • Rifat Ullah Khan
    • 2
  1. 1.Department of Livestock, Breeding and Genetics, Faculty of Animal Husbandry & Veterinary SciencesThe University of AgriculturePeshawarPakistan
  2. 2.Department of Animal Health, Faculty of Animal Husbandry & Veterinary SciencesThe University of AgriculturePeshawarPakistan

Personalised recommendations