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The frequency of neuropathic pain in Turkish patients with low back pain: a cross-sectional study

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Abstract

The aim of this study was to evaluate the frequency of neuropathic pain (NP) in patients with low back pain (LBP) and the relationship of NP with demographic characteristics and pain duration. Four hundred and forty patients were evaluated with respect to NP. Demographic data were collected and Douleur Neuropathique 4 Questions (DN4) questionnaire was used to identify NP. Any difference in demographic characteristics or duration of pain was investigated between the patients with and without NP. Sociodemographic factors which are independently associated with NP were analyzed. According to DN4, 43.9% of the patients had NP. Mean age of the patients was 44.8 years (± 13.7). 343 (77.9%) of the patients had chronic LBP (more than 3 months). The patients with NP were older (p < 0.001), had higher BMI (p = 0.005) and longer LBP duration (p < 0.001) and had lower educational level (p 0.018). NP was significantly more common in unemployed patients and less common in high-activity employees (p 0.001). Logistic regression analyses identified that high-active workers’ risk of having NP was 1.76 times lesser than other groups (office workers, housewives and retired patients). Nearly half of the patients with LBP were accompanied by NP. It was remarkably more common in sedentary patients and patients with low socioeconomic status. High physical activity at work was found to decrease the risk of having NP. Clinicians should emphasize on exercise training as a therapeutic intervention while LBP is being treated.

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References

  1. Mehra M et al (2012) The burden of chronic low back pain with and without a neuropathic component: a healthcare resource use and cost analysis. J Med Econ 15(2):245–252

    Article  Google Scholar 

  2. Woolf CJ et al (1998) Towards a mechanism-based classification of pain? Pain 77(3):227–229

    Article  Google Scholar 

  3. Merskey NBH (ed) (1994) Part III: pain terms, a current list with definitions and notes on usage, in classification of chronic pain. IASP, Seattle, pp 209–214

    Google Scholar 

  4. Freynhagen R, Baron R (2009) The evaluation of neuropathic components in low back pain. Curr Pain Headache Rep 13(3):185–190

    Article  Google Scholar 

  5. Beith ID et al (2011) Identifying neuropathic back and leg pain: a cross-sectional study. Pain 152(7):1511–1516

    Article  Google Scholar 

  6. Morso L, Kent PM, Albert HB (2011) Are self-reported pain characteristics, classified using the PainDETECT questionnaire, predictive of outcome in people with low back pain and associated leg pain? Clin J Pain 27(6):535–541

    Article  Google Scholar 

  7. Kaki AM, El-Yaski AZ, Youseif E (2005) Identifying neuropathic pain among patients with chronic low-back pain: use of the Leeds Assessment of Neuropathic Symptoms and Signs pain scale. Reg Anesth Pain Med 30(5):422–428

    PubMed  Google Scholar 

  8. Calik YCA (2015) The evaluation of the effect of neuropathic pain on functional disability in patients with chronic low back pain. Turk J Osteoporos 21:122–126

    Article  Google Scholar 

  9. Attal N et al (2011) The neuropathic components of chronic low back pain: a prospective multicenter study using the DN4 Questionnaire. J Pain 12(10):1080–1087

    Article  Google Scholar 

  10. Bouhassira D et al (2005) Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain 114(1–2):29–36

    Article  Google Scholar 

  11. Unal-Cevik I, Sarioglu-Ay S, Evcik D (2010) A comparison of the DN4 and LANSS questionnaires in the assessment of neuropathic pain: validity and reliability of the Turkish version of DN4. J Pain 11(11):1129–1135

    Article  Google Scholar 

  12. Freynhagen R et al (2006) painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 22(10):1911–1920

    Article  Google Scholar 

  13. Bouhassira D et al (2008) Prevalence of chronic pain with neuropathic characteristics in the general population. Pain 136(3):380–387

    Article  Google Scholar 

  14. Schmidt CO et al (2009) Modelling the prevalence and cost of back pain with neuropathic components in the general population. Eur J Pain 13(10):1030–1035

    Article  Google Scholar 

  15. Torrance N et al (2006) The epidemiology of chronic pain of predominantly neuropathic origin Results from a general population survey. J Pain. 7(4):281–289

    Article  Google Scholar 

  16. Gudala K et al (2017) High prevalence of neuropathic pain component in patients with low back pain: evidence from meta-analysis. Pain Physician 20(5):343–352

    PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Istanbul Medeniyet University, Istanbul, Turkey

    Belgin Erhan

  2. Department of Physical Medicine and Rehabilitation, Istanbul Gaziosmanpasa Training and Research Hospital, 885. Street Mevlana District, Gaziosmanpasa, 34255, Istanbul, Turkey

    Kevser Gumussu, Belgin Kara, Gül Tuğba Bulut & Ebru Yılmaz Yalçınkaya

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  1. Belgin Erhan
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  2. Kevser Gumussu
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  3. Belgin Kara
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  4. Gül Tuğba Bulut
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  5. Ebru Yılmaz Yalçınkaya
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Correspondence to Kevser Gumussu.

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All procedures performed in this study are in accordance with ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments.

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Erhan, B., Gumussu, K., Kara, B. et al. The frequency of neuropathic pain in Turkish patients with low back pain: a cross-sectional study. Acta Neurol Belg 121, 873–877 (2021). https://doi.org/10.1007/s13760-020-01285-7

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  • DOI: https://doi.org/10.1007/s13760-020-01285-7

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