Acta Neurologica Belgica

, Volume 119, Issue 1, pp 119–121 | Cite as

Primary central nervous system lymphoma revealed by multiple intraventricular mass lesions

  • Marie Philippart
  • Nicolas Mulquin
  • Thierry Gustin
  • Caroline Fervaille
  • Frédéric LondonEmail author

A 71-year-old man was admitted in our institution with a 1-month history of vertigo, vomiting, and weight loss. He had no relevant medical history. On admission, the patient was significantly disoriented and we observed a severe impairment of short-term memory. He was able to walk without aid. He needed help to wash and get dressed. Cranial nerves, motor, sensory, and cerebellar examination was normal.

Blood tests including basic metabolic panel, liver function panel, thyroid studies, markers of inflammation, vitamin B12, and folate were all normal, and infectious serum tests including HIV were negative. The patient had no immunodeficiency. He underwent contrast-enhanced brain magnetic resonance imaging (MRI) demonstrating multiple homogeneously enhancing intraventricular mass lesions, involving the whole ventricular system (Fig. 1). Cerebrospinal fluid (CSF) analysis showed lymphocytic pleocytosis (115 cells/mm³; N ≤ 5) with increased protein (5.6 g/l; N: 15–45) and...


Intraventricular mass lesions CNS lymphoma MRI 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

For this type of study, no informed consent is required.


  1. 1.
    Ostrom QT, Gittleman H, Xu J et al (2016) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2009–2013. Neuro Oncol 18:v1–v75CrossRefGoogle Scholar
  2. 2.
    Bokhari R, Ghanem A, Alahwal M, Baeesa S (2013) Primary isolated lymphoma of the fourth ventricle in an immunocompetent patient. Case Rep Oncol Med 2013:614658Google Scholar
  3. 3.
    Funaro K, Bailey KC, Aguila S, Agosti SJ, Vaillancourt C (2014) A case of intraventricular primary central nervous system lymphoma. J Radiol Case Rep 8:1–7Google Scholar
  4. 4.
    Hsu HI, Lai PH, Tseng HH, Hsu SS (2015) Primary solitary lymphoma of the fourth ventricle. Int J Surg Case Rep 14:23–25CrossRefGoogle Scholar

Copyright information

© Belgian Neurological Society 2018

Authors and Affiliations

  • Marie Philippart
    • 1
  • Nicolas Mulquin
    • 2
  • Thierry Gustin
    • 3
  • Caroline Fervaille
    • 4
  • Frédéric London
    • 1
    Email author
  1. 1.Service de NeurologieCHU UCL Namur, Université catholique de LouvainYvoirBelgium
  2. 2.Service de RadiologieCHU UCL Namur, Université catholique de LouvainYvoirBelgium
  3. 3.Service de NeurochirurgieCHU UCL Namur, Université catholique de LouvainYvoirBelgium
  4. 4.Service d’Anatomie-PathologiqueCHU UCL Namur, Université catholique de Louvain,YvoirBelgium

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