Acta Neurologica Belgica

, Volume 118, Issue 2, pp 327–329 | Cite as

Longitudinally extensive spinal cord lesions: not always neuromyelitis optica

  • Antoine Ruyssen
  • Nicolas Mulquin
  • Thierry Gustin
  • Caroline Fervaille
  • Frédéric London
Letter to the Editor


Diagnosis of spinal cord lesions can be challenging. Longitudinally extensive transverse myelitis is a frequent manifestation of inflammatory central nervous system (CNS) disorders such as neuromyelitis optica and neurosarcoidosis. However, it is not pathognomonic of these diseases which can be mimicked by others disorders. We present a case of primary CNS lymphoma (PCNSL) which initially manifested as a longitudinally extensive transverse myelopathy (LETM).

Case report

A 54-year-old man was admitted in our department because of subacute onset of paraparesis, numbness of the lower limbs and bladder dysfunction. His medical history was notable for seropositive rheumatoid arthritis treated with abatacept and prednisone, and in remission for 3 years. On admission, neurological examination showed sensory level T6, generalized hyperreflexia and bilateral extensor plantar response. The patient was not able to walk. He reported asthenia and loss of weight over the previous six...


Longitudinally extensive myelopathy Spinal cord Lymphoma MRI 


Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest regarding this case report.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from the patient included in the study.


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Copyright information

© Belgian Neurological Society 2018

Authors and Affiliations

  • Antoine Ruyssen
    • 1
  • Nicolas Mulquin
    • 2
  • Thierry Gustin
    • 3
  • Caroline Fervaille
    • 4
  • Frédéric London
    • 1
  1. 1.Service de NeurologieCHU UCL Namur Site Godinne, Université Catholique de LouvainYvoirBelgium
  2. 2.Service de RadiologieCHU UCL Namur Site Godinne, Université Catholique de LouvainYvoirBelgium
  3. 3.Service de NeurochirurgieCHU UCL Namur Site Godinne, Université Catholique de LouvainYvoirBelgium
  4. 4.Service d’Anatomie-PathologiqueCHU UCL Namur Site Godinne, Université Catholique de LouvainYvoirBelgium

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