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Autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: a case series

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Abstract

Antibodies against glutamic acid decarboxylase (GAD) are associated with various neurologic conditions described in patients including stiff person syndrome, cerebellar ataxia, refractory epilepsy, limbic and extralimbic encephalitis. GAD antibodies-related limbic encephalitis cases are well described; reports of extralimbic involvement are limited. We describe four cases of GAD antibody-related autoimmune encephalitis. Three of them had extralimbic involvement and only one had limbic encephalitis.

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Funding

The authors received no financial support for the research, authorship, and/or publication of this article.

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Authors and Affiliations

  1. Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey

    Faruk Incecik, Ozlem M. Herguner & Seyda Besen

  2. Department of Pediatric Immunology, Cukurova University Faculty of Medicine, Adana, Turkey

    Mustafa Yılmaz

Authors
  1. Faruk Incecik
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  2. Ozlem M. Herguner
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  3. Seyda Besen
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  4. Mustafa Yılmaz
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Correspondence to Faruk Incecik.

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The authors declared no potential conflict of interest with respect to the research, authorship, and/or publication of this article.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from the parents of the child included in the study.

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Incecik, F., Herguner, O.M., Besen, S. et al. Autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: a case series. Acta Neurol Belg 118, 411–414 (2018). https://doi.org/10.1007/s13760-018-0880-5

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  • DOI: https://doi.org/10.1007/s13760-018-0880-5

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