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Synthesis and characterization of eggshell membrane polymer-TiO2 nanocomposite for newly synthesized ionic liquid release

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Abstract

This work includes the synthesis of a new ionic liquid (IL) derived from benzisothiazolinon (Bit) by the reaction of benzisothiazolinon with HCl at room temperature. This ionic liquid (BitIL) was characterized using FTIR, 1HNMR, 13C-NMR, and elemental analysis. Furthermore, eggshell membrane protein polymer (ESMP) was used as a natural polymer to prepare its nanocomposite with titanium oxide nanoparticles (TiO2 NPs) (ESMP-TiO2). At the end of the synthesis route, the as-prepared benzisothiazolinon ionic liquid (BitIL) was grafted on the surface of the nanocomposite to synthesis benzisothiazolinon ionic liquid@ eggshell membrane protein polymer–titanium oxide (BitIL@ESMP-TiO2) nanocomposite by the one-pot method. The BitIL@ESMP-TiO2 nanocomposite was characterized using FTIR, XRD, and TEM. Moreover, the kinetics of in vitro release of BitIL from BitIL@ESMP-TiO2 was studied using Korsmeyer and Peppas equation at two different temperatures and pHs. From the results, it was found that the BitIL released from ESMP-TiO2 was about 85%, at 37 °C. Furthermore, the pH = 1.2 (stomach acidity) produced n values of 0.645 and 0.761, indicating the prevalence of anomalous type, whereas the pH = 7.2 (blood acidity) produced quasi-Fickian type diffusion.

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Authors and Affiliations

  1. Department of Nursing, Al-Hadi University College, Baghdad, Iraq

    Mustafa A. Alheety

  2. Department of Chemistry, College of Science, Diyala University, Diyala, Iraq

    Abdulwahhab H. Majeed & Leqaa A. Mohammed

  3. Department of Medical Laboratory Technology, Imam Ja’afar Al-Sadiq University, Kirkuk, Iraq

    Aisha H. Ali

  4. Department of Chemistry, College of Science, Tokat Gaziosmanpsasa University, 60250, Tokat, Turkey

    Ali Destagul

  5. Department of Physics, Center of Excellence on Solar Cells and Renewable Energy, School of Basic Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, 201308, India

    Pramod K. Singh

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  1. Mustafa A. Alheety
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Correspondence to Mustafa A. Alheety.

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Alheety, M.A., Majeed, A.H., Ali, A.H. et al. Synthesis and characterization of eggshell membrane polymer-TiO2 nanocomposite for newly synthesized ionic liquid release. J IRAN CHEM SOC 19, 4005–4015 (2022). https://doi.org/10.1007/s13738-022-02584-x

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