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Synthesis of novel organotin(IV) complex for multiple applications: as biologically potent and single molecular precursor

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Abstract

This work reports a facile solution-based synthesis of novel single molecular precursor (SMP), triphenylstannyl 4-((4-bromophenyl) amino)-4-oxobut-2-enoate complex (2). The as-prepared SMP was characterized by single crystal X-rays diffraction, elemental analysis, 1H NMR, 13C NMR and Mass spectrometry. The thermal properties of as-prepared SMP were assessed by thermogravimetric analysis and differential calorimetry. The as-prepared complex showed excellent DNA binding property in vivo experiments. The as-prepared complex (2) also revealed good antileishmanial and anticancer properties. Lastly, high-quality transparent SnO2 thin films were obtained by aerosol-assisted chemical vapors deposition on common window glass. The morphological and structural studies of as-deposited thin films were performed by XRD and FE-SEM.

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Authors and Affiliations

  1. Department of Chemistry, Allama Iqbal Open University, Islamabad, Pakistan

    Arshad Farooq Butt & Moazzam Hussain Bhatti

  2. Materials Laboratory, Department of Chemistry, Mirpur University of Science and Technology (MUST), Mirpur, 10250, AJK, Pakistan

    Arshad Farooq Butt, Muhammad Aamir & Muhammad Aziz Choudhary

  3. National Center for Nanotechnology, Department of Metallurgy and Material Engineering, Pakistan Institute of Engineering and Applied Sciences, Islamabad, Pakistan

    Jamil Ahmad

  4. Department of Physics, University of Sargodha, Sargodha, Punjab, Pakistan

    Muhammad Nawaz Tahir

Authors
  1. Arshad Farooq Butt
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  2. Muhammad Aamir
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  3. Moazzam Hussain Bhatti
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  4. Muhammad Aziz Choudhary
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  5. Jamil Ahmad
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  6. Muhammad Nawaz Tahir
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Correspondence to Arshad Farooq Butt or Moazzam Hussain Bhatti.

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Butt, A.F., Aamir, M., Bhatti, M.H. et al. Synthesis of novel organotin(IV) complex for multiple applications: as biologically potent and single molecular precursor. J IRAN CHEM SOC 18, 307–315 (2021). https://doi.org/10.1007/s13738-020-02027-5

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  • DOI: https://doi.org/10.1007/s13738-020-02027-5

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