Abstract
Three pyrazole Schiff bases (E)-2-(((1H-pyrazol-3-yl)imino)methyl)-6-methoxyphenol (1), (Z)-N-(4-bromobenzylidene)-1H-pyrazol-3-amine (2), and (E)-2-(((1H-pyrazol-3-yl)imino) methyl)-4,6-dibromophenol (3) have been synthesized and characterized by elemental analyses, FT-IR, 1HNMR. The molecular structures were confirmed by X-ray structural studies, and investigated intermolecular interactions in building different supramolecular architectures. The title compounds are associated through hydrogen bonds, π-stacking interactions and further connected into hydrogen-bonded supramolecular layers and are responsible as well for the strengthening of the molecular assembly. In addition, the title compounds were also tested for their ability to inhibit the growth of C. albicans and Gram-negative bacteria. It was worthwhile to note that 1 and 3 could be used as potential antibacterial agents.
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Acknowledgements
We gratefully acknowledge the Key Research Project of Natural Science from Provincial Bureau of Education, Anhui, China (KJ2017A572), the National Natural Science Foundation of China (20801012), and the financial support from Jiangsu Ainaji Neoenergy Science and Technology Co., Ltd (8507040091).
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Feng, C., Guo, JJ., Sun, LN. et al. Pyrazole Schiff bases cross-linked supramolecules: structural elucidation and antibacterial activity. J IRAN CHEM SOC 15, 2871–2876 (2018). https://doi.org/10.1007/s13738-018-1473-1
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DOI: https://doi.org/10.1007/s13738-018-1473-1