Journal of the Iranian Chemical Society

, Volume 15, Issue 7, pp 1593–1601 | Cite as

Polyaniline/graphene oxide nanocomposite as a sorbent for extraction and determination of nicotine using headspace solid-phase microextraction and gas chromatography–flame ionization detector

  • Iraj Salimikia
  • Rouhollah Heydari
  • Fatemeh Yazdankhah
Original Paper


A solid-phase microextraction fiber was prepared by polyaniline/graphene oxide nanocomposite as sorbent on the surface of a platinized stainless steel wire using electrospinning technique. The nanocomposite structure was characterized by scanning electron microscopy and Fourier transform infrared spectroscopy. The polyaniline/graphene oxide nanocomposite fiber was used for the determination of nicotine from tobacco samples using headspace solid-phase microextraction method and gas chromatography–flame ionization detection. Influential experimental variables on the extraction efficiency of nicotine, such as extraction time and temperature, humidity and desorption conditions, were evaluated and optimized. Under the optimal experimental conditions‚ the limit of detection, linear dynamic range, intraday and inter-days precisions were found to be 0.01 μg g−1, 0.05–700 µg g−1 (R2 = 0.996), 6.9 and 8.1%, respectively. Comparison of the polyaniline/graphene oxide nanocomposite sorbent with polyaniline and commercial fibers shows longer durability, larger capacity and higher extraction efficiency. The polyaniline/graphene oxide nanocomposite fiber was successfully applied for the determination of nicotine in tobacco samples.


Polyaniline/graphene oxide Headspace solid-phase microextraction Electrospinning Nicotine Gas chromatography 



The authors gratefully acknowledge the support of Lorestan University of Medical Sciences (Khorramabad, Iran).


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Copyright information

© Iranian Chemical Society 2018

Authors and Affiliations

  1. 1.Department of Pharmacognosy, Faculty of PharmacyLorestan University of Medical SciencesKhorramabadIran
  2. 2.Razi Herbal Medicines Research CenterLorestan University of Medical SciencesKhorramabadIran
  3. 3.Student Research CommitteeLorestan University of Medical SciencesKhorramabadIran

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