Enhanced antibacterial activity of functionalized graphene by azo-pyridinium compounds
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For enhancement of antibacterial properties, two azo compounds were grafted on the aminated graphene by using the imine linkage. The azo compounds included pyridinium unit with different alkyl long chains. The new nanohybrids were characterized by Fourier transform infrared spectra, X-ray powder diffraction, ultraviolet–visible, field emission scanning electron microscopy (FE-SEM), atomic force microscopy, zeta potential, and energy-dispersive X-ray spectroscopy. The hybrids were investigated for antibacterial effect against Staphylococcus aureus and Escherichia coli as models of Gram-positive and Gram-negative bacteria. The nanohybrids showed a significant effect on both bacteria. Destruction of the cell wall and discharge of intracellular contents could be detected from FE-SEM images of bacteria after exposed to nanohybrids. The nanohybrid with C10 alkyl chain in the pyridinium unit displayed the highest antibacterial activity.
KeywordsAntibacterial activity Graphene Imine linkage Pyridinium salt
We are grateful to the Lorestan University for financial support of this work.