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Application of chitosan matrix for delivery of rutin

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Abstract

Chitosan matrices are an alternative material to the food industry, due to its ability to release bioactive compounds through interconnected cavities. Chitosan is a biomaterial of excellence, because it shows unique features, such as biocompatibility, non-toxicity, bactericidal action and the ability to associate with other compounds. Thus, this study aimed the development of chitosan matrices incorporated with rutin, as well as the evaluation of rutin release. Chitosan matrices with rutin were prepared by the coacervation method in alkaline solution and subsequently characterized through FT-IR, TG-DSC, X-ray diffraction, SEM and further submitted to rutin release assay. Results show the effectiveness in the incorporation of rutin into the polymeric matrix. The polymeric matrix with rutin can quickly release it, which provides a wide range of applications, such as carrier of rutin as a micronutrient food additive.

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Authors and Affiliations

  1. Materials Research Laboratory (LEMat), Universidade Federal de Mato Grosso (UFMT), Campus Universitário do Araguaia, BR-070, km 5, Barra do Garças, MT, 78600-000, Brazil

    Iza Natalia Queiroz de Arruda, Valdir Aniceto Pereira Jr. & Ricardo Stefani

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  1. Iza Natalia Queiroz de Arruda
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  2. Valdir Aniceto Pereira Jr.
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  3. Ricardo Stefani
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Correspondence to Ricardo Stefani.

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de Arruda, I.N.Q., Pereira, V.A. & Stefani, R. Application of chitosan matrix for delivery of rutin. J IRAN CHEM SOC 14, 561–566 (2017). https://doi.org/10.1007/s13738-016-1004-x

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  • DOI: https://doi.org/10.1007/s13738-016-1004-x

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