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One-pot insertion of chalcones into the benzoylacetone backbone

Abstract

Interaction of 1-phenylbutane-1,3-dione and chalcones in the presence of a base gives, in one step, good to high yields cyclic and unusual acyclic insertion products in ratios which depend on substrate, catalyst, and reaction conditions. All the synthesized compounds are characterized using IR, 1H and 13C NMR spectroscopies, ESI–MS, and single-crystal X-ray diffraction (for one compound) analysis.

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Acknowledgments

This work has been partially supported by the Baku State University, Azerbaijan.

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Correspondence to Kamran T. Mahmudov.

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Below is the link to the electronic supplementary material.

13738_2015_705_MOESM1_ESM.doc

Supplementary material 1 (DOC 4736 kb) Supplementary data (copies of 1H and 13C NMR spectra for all compounds) associated with this article can be found, in the online version, at http://dx.doi.org/10

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Naghiyev, F.N., Gurbanov, A.V., Maharramov, A.M. et al. One-pot insertion of chalcones into the benzoylacetone backbone. J IRAN CHEM SOC 13, 1–6 (2016). https://doi.org/10.1007/s13738-015-0705-x

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Keywords

  • Michael addition
  • Chalcone
  • Benzoylacetone
  • Active methylene compounds