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Journal of the Iranian Chemical Society

, Volume 11, Issue 4, pp 1067–1074 | Cite as

An efficient and facile regioselective synthesis of new substituted (E)-1-(3-aryl-7,8-dihydrocinnoline-5(6H)-ylidene)hydrazines and (1E,2E)-1,2-bis(3-aryl-7,8-dihydrocinnoline-5(6H)-ylidene)hydrazines

  • Jabbar KhalafyEmail author
  • Mahnaz Ezzati
  • Mehdi Rimaz
  • Ahmad Poursattar Marjani
  • Hooman Yaghoobnejad Asl
Original Paper

Abstract

A study concerning the new substituted cinnoline synthesis is described. The use of a one-pot three-component method allows a simple regioselective and efficient synthesis of cinnoline derivatives via reaction of arylglyoxals with 1,3-cyclohexanedione and dimedone in the presence of hydrazine hydrate.

Keywords

Arylglyoxal Cinnoline 1,3-Cyclohexanedione Dimedone One-pot Regioselective 

Notes

Acknowledgments

The authors are grateful to Urmia University for financial support and to Dr. A. Choudhury (Missouri University of Science and Technology, USA) for his assistance with X-ray crystallography.

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Copyright information

© Iranian Chemical Society 2013

Authors and Affiliations

  • Jabbar Khalafy
    • 1
    Email author
  • Mahnaz Ezzati
    • 1
  • Mehdi Rimaz
    • 2
  • Ahmad Poursattar Marjani
    • 1
  • Hooman Yaghoobnejad Asl
    • 3
  1. 1.Department of Organic Chemistry, Faculty of ChemistryUrmia UniversityUrmiaIran
  2. 2.Department of ChemistryPayame Noor UniversityTehranIran
  3. 3.Department of ChemistryMissouri University of Science and TechnologyRollaUSA

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