CEN Case Reports

, Volume 7, Issue 1, pp 98–100 | Cite as

Membranous glomerulonephritis with an LMNA mutation

  • Kumi Fujita
  • Kazuhiro Hatta
Case Report


We had encountered the case of membranous glomerulonephritis (MGN) with dilated cardiomyopathy due to LMNA gene mutation. LMNA mutation was known as a cause of ‘laminopathy’ such as dilated cardiomyopathy, muscular dystrophy, neuropathy and so on. LMNA gene might be a candidate of genetic basis in cryptogenic MGN.


Membranous glomerulonephritis Dilated cardiomyopathy Lamin A/C LMNA 



We would like to thank Dr. Kazuaki Kaitani and Dr. Naoaki Onishi, department of cardiology, Japanese Red Cross Otsu Hospital, Japan, for their great contribution. Furthermore, we thank Dr. Yoichiro Kobashi and Mr. Shiomi Yoshida, Tenri Institute of Medical Research, Japan for their help with the histological analyses.

Compliance with ethical standards

Conflict of interest

All the authors have declared that no conflict of interest exists.

Human and animal rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Informed consent

Informed consent was obtained from the patient for being included in the study.


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Copyright information

© Japanese Society of Nephrology 2018

Authors and Affiliations

  1. 1.Department of Diagnostic PathologyTenri HospitalTenriJapan
  2. 2.Department of General MedicineTenri HospitalTenriJapan

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