Skip to main content

Mobile self-management guide for young men with mild hemophilia in cases of minor injuries

Abstract

Hemophilia is a group of inherited disorders where a defect or absence of a clotting factor protein limits the ability of the blood to clot following injury. The most common form is Hemophilia A; it is classified as severe, moderate or mild. Those with severe and moderate Hemophilia are likely to experience bleeding into joints and muscles following minor injury and are advised to limit participation in rough activities. Those with milder disorders usually experience bleeds only after significant injury, and may participate in vigorous sports with few consequences. As a result, they sometimes ‘forget’ that they have Hemophilia, and are slow to recognize injuries which may require treatment. In our ongoing project, we designed a mobile app which is a self-assessment guide for young men with mild hemophilia. The mobile application guides the user in assessing suspected bleeds, applying appropriate first aid, and locating the nearest hemophilia treatment center. In this paper, we detail the architectural design of the mobile app (“HIRT?”). We proposed a three-layered distributed system architecture comprised of the mobile devices, a cloud-oriented proxy and a database server where user feedback is stored for further analysis. The proxy framework is designed to address the challenges of network latency in mobile environments since the primary means of communication is over wireless media. Preliminary evaluation of the proposed system shows high performance boost in terms of the minimization of latency. Furthermore, the usability test shows that the application is convenient to use by both mobile techies and non-techies.

This is a preview of subscription content, access via your institution.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Notes

  1. http://xamarin.com/.

References

  • Arunachalan B, Light J (2008) Agent-based mobile middleware architecture (AMMA) for patient-care clinical data messaging using wireless networks. In: Proceedings of the 2008 12th IEEE/ACM international symposium on distributed simulation and real-time applications (DS-RT ‘08). IEEE Computer Society, Washington, DC, USA, 326–329. doi: 10.1109/DS-RT.2008.50

  • Boukerche A, Owens H (2005) Media synchronization and QoS packet scheduling algorithms for wireless systems. Mob Netw Appl 10(1–2):233–249

    Article  Google Scholar 

  • Canadian Hemophilia Standards Group (2007) Canadian comprehensive care standards for hemophilia and other inherited bleeding disorders, 1st edn. http://www.ahcdc.ca/documents/CanadianHemophiliaStandardsFirstEdition070612_1.pdf

  • Choi M, Kim Y, Chang J (2005) Transaction-centric split synchronization mechanism for mobile e-business applications. Data engineering issues in E-Commerce, 2005. Proceedings. International workshop on, vol., no., pp 112–118, 9 April 2005

  • Choi E, Bae CS, Lee J (2012) Data synchronization between adjacent user devices for personal cloud computing. consumer electronics (ICCE), 2012 IEEE international conference on, vol., no., pp 49–50, 13–16 Jan 2012, doi: 10.1109/ICCE.2012.6161732

  • Gad S (2010) Data synchronization architectural pattern for ubiquitous learning systems. In: Programming support innovations for emerging distributed applications (PSI EtA ‘10). ACM, New York, NY, USA, Article 2, 5 pages. doi: 10.1145/1940747.1940749

  • Gantsou D (2003) A DSA model for data access in self-organizing systems. In: Proceedings of the 2003 annual ACM SIGAda international conference on Ada: the engineering of correct and reliable software for real-time \& distributed systems using ada and related technologies (SigAda ‘03). ACM, New York, NY, USA, 25–28. doi: 10.1145/958420.958425

  • Hansen FA, Grønbæk K (2010) UrbanWeb: a platform for mobile context-awaresocial computing. In: Proceedings of the 21st ACM conference on hypertext and hypermedia (HT ‘10). ACM, New York, NY, USA, 195–200. doi: 10.1145/1810617.1810651

  • Khan AM, Chabridon S, Beugnard A (2007) Synchronization medium: a consistency maintenance component for mobile multiplayer games. In: Proceedings of the 6th ACM SIGCOMM workshop on network and system support for games (NetGames ‘07). ACM, New York, NY, USA, 99–104. doi: 10.1145/1326257.1326275

  • Klingelhuber P, Mayrhofer R (2011) Private notes: encrypted XML notes synchronization and sharing with untrusted web services. In: Proceedings of the 13th international conference on information integration and web-based applications and services (iiWAS ‘11). ACM, New York, NY, USA, 254–261. doi: 10.1145/2095536.2095579

  • Koskimies O (2005) Using data item relationships to adaptively select data for synchronization. In: Lea Kutvonen, Nancy Alonistioti (eds) Proceedings of the 5th IFIP WG 6.1 international conference on distributed applications and interoperable systems (DAIS’05). Springer-Verlag, Berlin, Heidelberg, 220–225. doi: 10.1007/11498094_20

  • Kumar R, Stain AM, Hilliard P, Carcao M (2013) Consequences of delayed therapy for sports-related bleeds in patients with mild-to-moderate haemophilia and type3 von Willebrand’s disease not on prophylaxis. Haemophilia 19:e256–e269

    Article  Google Scholar 

  • Lam F, Lam N, Wong R (2002) Efficient synchronization for mobile XML data. In: Proceedings of the eleventh international conference on information and knowledge management (CIKM ‘02). ACM, New York, NY, USA, 153–160. doi: 10.1145/584792.584820

  • Lomotey RK, Deters R (2012) Using a cloud-centric middleware to enable mobile hosting of web services. Procedia Computer Science, vol 10, pp 634–641, ISSN 1877-0509. 10.1016/j.procs.2012.06.081 http://www.sciencedirect.com/science/article/pii/S1877050912004383

  • Lomotey RK, Jamal S, Deters R (2012a) SOPHRA: a mobile web services hosting infrastructure in mHealth. Mobile Services (MS), 2012 IEEE first international conference on, vol., no., pp 88–95, 24–29. doi: 10.1109/MobServ.2012.14

  • Lomotey R, Kazi R, Deters R (2012b) Near real-time medical data dissemination in m-Health. In: Proceedings of the international conference on management of emergent digital ecosystems (MEDES ‘12). ACM, New York, NY, USA, 67–74. doi: 10.1145/2457276.2457290

  • Marforio C, Ritzdorf H, Francillon A, Capkun S (2012) Analysis of the communication between colluding applications on modern smartphones. In: Proceedings of the 28th annual computer security applications conference (ACSAC ‘12). ACM, New York, NY, USA, 51–60. doi: 10.1145/2420950.2420958

  • Mulder K (2011) The Mild Hemophilia Project: questionnaire results from Calgary. Hemophilia Today 46:3

    Google Scholar 

  • Nilson J, Mulder K (2012) A new self-assessment pathway tool for young men with mild hemophilia A and B who experience musculoskeletal bleeds. Poster; WFH Congress, France

    Google Scholar 

  • Nilson J, Schachter C, Mulder K et al (2012) A qualitative study identifying the knowledge, attitudes and behaviours of young men with mild haemophilia. Haemophilia 18:e120–e125

    Article  Google Scholar 

  • Querol F, Aznar JA, Haya S, Cid A (2002) Musculoskeletal injuries in patients with mild hemophilia. Poster; World Federation of Hemophilia Congress, France

    Google Scholar 

  • Ratner D, Reiher P, Popek GJ (2004) Roam: a scalable replication system for mobility. Mob Netw Appl 9(5):537–544

    Article  Google Scholar 

  • Sain M, Lee H, Chung W (2009) Middleware in ubiquitous computing system with MedRec architecture. In: Proceedings of the 2nd international conference on interaction sciences: information technology, culture and human (ICIS ‘09). ACM, New York, NY, USA, 149–154. doi: 10.1145/1655925.1655953

  • van Wanroij H, Dielen I, Amtari M, Laros B, Novakova I (2010) Mild hemophilia and trauma. Poster; World Federation of Hemophilia Congress, France

    Google Scholar 

  • Veeraraghavan K, Ramasubramanian V, Rodeheffer TL, Terry DB, Wobber T (2009) Fidelity-Aware Replication for Mobile Devices. In: Mobisys 2009: Proceedings of the 7th international conference on mobile systems, applications, and services, June 2009

  • WFH (2012) Guidelines for the management of hemophilia, 2nd edn. http://www.wfh.org/en/resources/wfh-treatment-guidelines. Accessed 11 June 2014

  • Xie J, Yu D, Ma S (2008) A Novel Enterprise Mobile E-mail System Using the SyncML Protocol. In: Proceedings of the Seventh IEEE/ACIS International Conference on computer and information science (icis 2008) (ICIS ‘08). IEEE Computer Society, Washington, DC, USA, 391–396. doi: 10.1109/ICIS.2008.10

Download references

Acknowledgments

We will like to thank the following individuals and agencies: BHAP—The Bayer Hemophilia Award Program (BHAP) MITACS Accelerate Program, and The Canadian Hemophilia Society (CHS) for their support on hosting the App. Also, thanks to Prof. Reda Alhajj, the reviewers and editors of Network Modeling Analysis in Health Informatics and Bioinformatics.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Richard K. Lomotey.

Appendix

Appendix

See Table 2.

Table 2 Comparing HIRT? to other frameworks

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Lomotey, R.K., Mulder, K., Nilson, J. et al. Mobile self-management guide for young men with mild hemophilia in cases of minor injuries. Netw Model Anal Health Inform Bioinforma 3, 64 (2014). https://doi.org/10.1007/s13721-014-0064-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s13721-014-0064-z

Keywords

  • Mobile devices
  • Hemophilia
  • Proxy
  • Cloud computing
  • Distributed system
  • Database