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A case of a pregnant woman with locally advanced cervical esophageal cancer treated with definitive chemoradiotherapy

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Abstract

The information of definitive radiotherapy for a pregnant woman with malignancy was limited; however, it was reported to be potentially feasible with minimal risks. We performed definitive chemoradiotherapy for a pregnant woman with locally advanced cervical esophageal cancer. Feasibility of radiotherapy and safety of fetus were confirmed by the phantom study estimating fetal dose, and monitoring it in each radiotherapy session. The planned chemoradiotherapy completely eradicated esophageal cancer while preserving her laryngopharyngeal function. A female infant was delivered by cesarian section after planned chemoradiotherapy, and she grew without any apparent disorders 2 years after chemoradiotherapy. Chemoradiotherapy might be one of the treatment options for a pregnant woman with cervical esophageal cancer especially wishing the preservation of laryngopharyngeal function.

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Authors and Affiliations

  1. Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan

    Yudai Tateishi, Katsuyuki Sakanaka, Hideaki Hirashima, Nobutaka Mukumoto, Hiroyuki Inoo, Kota Fujii, Tomohiro Ono & Takashi Mizowaki

  2. Division of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan

    Mitsuhiro Nakamura

  3. Division of Clinical Radiology Service, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan

    Manabu Nakata

  4. Department of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan

    Kaoru Kawasaki, Hirohiko Tani & Masaki Mandai

Authors
  1. Yudai Tateishi
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  2. Katsuyuki Sakanaka
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  3. Hideaki Hirashima
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  4. Nobutaka Mukumoto
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  5. Hiroyuki Inoo
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  6. Kota Fujii
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  7. Tomohiro Ono
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  8. Mitsuhiro Nakamura
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  9. Manabu Nakata
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  10. Kaoru Kawasaki
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  11. Hirohiko Tani
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  12. Masaki Mandai
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  13. Takashi Mizowaki
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Corresponding author

Correspondence to Katsuyuki Sakanaka.

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The authors declare that they have no conflict of interest.

Research involving human participants and/or animals

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

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Informed consent was obtained from the patient included in the study.

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Tateishi, Y., Sakanaka, K., Hirashima, H. et al. A case of a pregnant woman with locally advanced cervical esophageal cancer treated with definitive chemoradiotherapy. Int Canc Conf J 11, 292–297 (2022). https://doi.org/10.1007/s13691-022-00564-9

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  • DOI: https://doi.org/10.1007/s13691-022-00564-9

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