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Clinical Epidemiology of Gestational Trophoblastic Disease

  • Management of Gestational Trophoblastic Diseases (A Cheung, Section Editor)
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Abstract

The epidemiology of gestational trophoblastic disease (GTD) is not well defined. The rarity of the disease and challenges in data collection limit interpretation of incidence data. Incidence of GTD appears to be influenced by geographic region, with the highest rates occurring in Southeast Asia and Japan. Risk factors for molar pregnancy include extremes of maternal age, reproductive history, and dietary deficiencies. Risk factors for choriocarcinoma include age, ethnicity, history of complete molar pregnancy, and ABO blood group status. With improvements in socioeconomic conditions and diet as well as diagnosis and management of GTD, the incidence of trophoblastic disease is declining worldwide. Future studies should focus on mechanisms by which risk factors influence development and progression of GTD.

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Conflict of Interest

Anna E. Strohl and John R. Lurain declare that they have no conflict of interest

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. John I. Brewer Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Anna E. Strohl & John R. Lurain

  2. Prentice Women’s Hospital, Northwestern University Feinberg School of Medicine, 250 East Superior Street, Suite 05-2168, Chicago, IL, 60611, USA

    John R. Lurain

Authors
  1. Anna E. Strohl
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  2. John R. Lurain
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Correspondence to John R. Lurain.

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Strohl, A.E., Lurain, J.R. Clinical Epidemiology of Gestational Trophoblastic Disease. Curr Obstet Gynecol Rep 3, 40–43 (2014). https://doi.org/10.1007/s13669-013-0070-7

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  • DOI: https://doi.org/10.1007/s13669-013-0070-7

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