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Impact of Energy Drinks on Health and Well-being


Purpose of Review

Energy drinks and energy shots are functional supplements with higher caffeine content marketed toward adolescents and young adults with the intention of boosting energy. Parallel to its rising popularity, there are safety concerns with the consumption of these beverages. Herein, we reviewed the impact these supplements produce on health and well-being.

Recent Findings

Most of the promoted benefits of the beverages can be attributed to caffeine. The physiologic effects, if any, of other ingredients such as vitamins and herbal extracts are unclear. The presence of a higher caffeine content as compared to soft drinks may predispose to caffeine intoxication in susceptible individuals. Also, the practice of co-ingestion of these beverages with alcohol is still prevalent and associated with serious consequences.


Strict regulations (restriction of sales, clear warning labels, capping caffeine levels) and public education may help prevent the adverse outcomes from these beverages.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Care RP. Sports Drinks and Energy drinks for children and adolescents: are they appropriate? Pediatrics. 2011;127(6):1182–9.

    Article  Google Scholar 

  2. Heckman MA, Weil J, de Mejia EG. Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. J Food Sci. 2010;75(3)

  3. Accessed on 5.15.2018 [Internet]. Available from:

  4. Accessed on 5.15.2018 [Internet]. Available from:

  5. Accessed on 5.15.2018 [Internet]. Available from:

  6. Accessed on 5.15.2018 [Internet]. Available from:

  7. Accessed on 5.15.2018 [Internet]. Available from:

  8. Accessed on 5.15.2018 [Internet]. Available from:

  9. Accessed on 5.15.2018 [Internet]. Available from:

  10. Accessed on 5.15.2018 [Internet]. Available from:

  11. Accessed on 5.15.2018 [Internet]. Available from:

  12. Accessed on 5.15.2018 [Internet]. Available from:

  13. Accessed on 5.15.2018 [Internet]. Available from:

  14. Accessed on 5.15.2018 [Internet]. Available from:

  15. Accessed on 5.15.2018 [Internet]. Available from:

  16. Enriquez A, Frankel DS. Arrhythmogenic effects of energy drinks. J Cardiovasc Electrophysiol. 2017;28(6):711–7.

    Article  PubMed  Google Scholar 

  17. Thorlton J, Colby DA, Devine P. Proposed actions for the US food and drug administration to implement to minimize adverse effects associated with energy drink consumption. Am J Public Health. 2014;104(7):1175–80.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Lara B, Ruiz-Vicente D, Areces F, Abián-Vicén J, Salinero JJ, Gonzalez-Millán C, et al. Acute consumption of a caffeinated energy drink enhances aspects of performance in sprint swimmers. Br J Nutr. 2015;114(6):908–14.

    Article  PubMed  CAS  Google Scholar 

  19. Accessed on 5.15.2018 [Internet]. Available from:,-and-rarely-need-sports-drinks,-says-aap.aspx

  20. Heckman MA, Sherry K, de Mejia EG. Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr Rev Food Sci Food Saf. 2010;9(3):303–17.

    Article  CAS  Google Scholar 

  21. Reissig CJ, Strain EC, Griffiths RR. Caffeinated energy drinks-a growing problem. Drug Alcohol Depend. 2009;99(1–3):1–10.

    Article  PubMed  CAS  Google Scholar 

  22. Accessed on 5.15.2018 [Internet]. Available from:

  23. Accessed on 5.15.2018 [Internet]. Available from:

  24. Yvonne, M. Terryn, McElrath MSA, Patrick M., O’Malley, PhD, and Lloyd D. Johnston P. Energy drinks, soft drinks, and substance use among US secondary school students. J Addict Med 2012;8(1):6–17.

  25. Terry-McElrath YM, O’malley PM, Johnston LD. Energy drinks, soft drinks, and substance use among United States secondary school students. J Addict Med 8(1):6–13.

  26. Manchester J, Eshel I, Marion DW. The benefits and risks of energy drinks in young adults and military service members. Mil Med. 2017;182(7):e1726–33.

    Article  PubMed  Google Scholar 

  27. Fulgoni VL, Keast DR, Lieberman HR. Trends in intake and sources of caffeine in the diets of US adults: 2001-2010. Am J Clin Nutr. 2015;101(5):1081–7.

    Article  PubMed  CAS  Google Scholar 

  28. Costa BM, Hayley A, Miller P. Adolescent energy drink consumption: an Australian perspective. Appetite. 2016;105:638–42.

    Article  PubMed  Google Scholar 

  29. McLellan TM, Riviere LA, Williams KW, McGurk D, Lieberman HR. Caffeine and energy drink use by combat arms soldiers in Afghanistan as a countermeasure for sleep loss and high operational demands. Nutr Neurosci. 2018 Mar;11:1–10.

    Article  Google Scholar 

  30. Accessed on 5.15.2018 [Internet]. Available from:

  31. Seifert SM, Schaechter JL, Hershorin ER, Lipshultz SE. Health effects of energy drinks on children, adolescents, and Young Adults. Pediatrics. 2011;127(3):511–28.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Accessed on 5.15.2018 [Internet]. Available from:

  33. Sepkowitz KA. Energy drinks and caffeine-related adverse effects. JAMA. 2013;309(3):243–4.

    Article  PubMed  CAS  Google Scholar 

  34. Dawodu A, Cleaver K. Behavioural correlates of energy drink consumption among adolescents: a review of the literature. J Child Heal Care. 2017;21(4):446–62.

    Article  Google Scholar 

  35. Ha D, Song I, Jang G, Lee E-K, Shin J-Y. Use pattern and predictors of use of highly caffeinated energy drinks among South Korean adolescents: a study using the Health Belief Model. BMJ Open. 2017;7(9):e017224.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Hammond D, Reid JL, Zukowski S. Adverse effects of caffeinated energy drinks among youth and young adults in Canada: a Web-based survey. C open. 2018;6(1):E19–25.

    Article  Google Scholar 

  37. Peacock A, Bruno R, Ferris J, Winstock A. Energy drink use frequency among an international sample of people who use drugs: associations with other substance use and well-being. Drug Alcohol Depend. 2017;174:70–9.

    Article  PubMed  Google Scholar 

  38. Zucconi S, Volpato C, Adinolfi F, Gandini E, Gentile E, Loi A et al. Gathering consumption data on specific consumer groups of energy drinks.[Internet]. Available from:

  39. Oglesby LW, Amrani KA, Wynveen CJ, Gallucci AR. Do energy drink consumers study more? J Community Health. 2018;43(1):48–54.

    Article  PubMed  Google Scholar 

  40. Rao N, Spiller HA, Hodges NL, Chounthirath T, Casavant MJ, Kamboj AK, et al. An increase in dietary supplement exposures reported to US poison control centers. J Med Toxicol. 2017;13(3):227–37.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  41. SAMHSA. Update on Emergency Department visits involving energy drinks: a continuing public health concern. Drug Abus Warn Netw. 2013. Accessed on 5.15.2018 [Internet]. Available from:

  42. Ludden AB, O’Brien EM, Beliefs PKE. Behaviors, and contexts of adolescent caffeine use: a focus group study. Subst Use Misuse. 2017;52(9):1207–18.

    Article  PubMed  Google Scholar 

  43. Bashir D, Reed-Schrader E, Olympia RP, Brady J, Rivera R, Serra T, et al. Adverse effects associated with energy drink consumption in adolescents. Pediatr Emerg Care. 2016;32(11):751–5.

  44. Bonar EE, Cunningham RM, Polshkova S, Chermack ST, Blow FC, Walton MA. Alcohol and energy drink use among adolescents seeking emergency department care. Addict Behav. 2015;43:11–7.

    Article  PubMed  Google Scholar 

  45. Francis J, Martin K, Costa B, Christian H, Kaur S, Harray A, et al. Informing intervention strategies to reduce energy drink consumption in young people: findings from qualitative research. J Nutr Educ Behav 2017;49(9):724–733.e1.

  46. Accessed on 5.15.2018. Available from:

  47. Accessed on 5.15.2018. Available from:

  48. Accessed on 5.15.2018. Available from:

  49. Accessed on 5.15.2018 [Internet]. Available from:

  50. Accessed on 5.15.2018. Available from:

  51. Goldfarb M, Tellier C, Thanassoulis G. Review of published cases of adverse cardiovascular events after ingestion of energy drinks. Am J Cardiol. 2014;113(1):168–72.

    Article  PubMed  Google Scholar 

  52. Jacobson BH, Hester GM, Palmer TB, Williams K, Pope ZK, Sellers JH, et al. Effect of energy drink consumption on power and velocity of selected sport performance activities. J Strength Cond Res. 2018;32(6):1613–8.

    Article  PubMed  Google Scholar 

  53. Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev17(2):139–70.

  54. Wolk BJ, Ganetsky M, Babu KM. Toxicity of energy drinks. Curr Opin Pediatr. 2012;24(2):243–51.

    Article  PubMed  CAS  Google Scholar 

  55. de Sanctis V, Soliman N, Soliman AT, Elsedfy H, Di Maio S, El Kholy M, et al. Caffeinated energy drink consumption among adolescents and potential health consequences associated with their use: a significant public health hazard. Acta Biomed. 2017;88(2):222–31.

    PubMed  Google Scholar 

  56. Balogh A, Harder S, Vollandt R, Staib AH. Intra-individual variability of caffeine elimination in healthy subjects. Int J Clin Pharmacol Ther Toxicol. 1992;30(10):383–7.

    PubMed  CAS  Google Scholar 

  57. Accessed on 5.15.2018 [Internet]. Available from:

  58. Chaban R, Kornberger A, Branski N, Buschmann K, Stumpf N, Beiras-Fernandez A, et al. In-vitro examination of the positive inotropic effect of caffeine and taurine, the two most frequent active ingredients of energy drinks. BMC Cardiovasc Disord. 2017;17(1):1–8.

    Article  Google Scholar 

  59. • Souza DB, Del Coso J, Casonatto J, Polito MD. Acute effects of caffeine-containing energy drinks on physical performance: a systematic review and meta-analysis. Eur J Nutr. 2017;56(1):13–27. This systematic review analyzes the acute effects of caffeinated energy drinks on physical performance.

  60. Xu Y-J, Arneja AS, Tappia PS, Dhalla NS. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57–65.

    PubMed  PubMed Central  Google Scholar 

  61. Jeffries O, Hill J, Patterson SD, Waldron M. Energy drink doses of caffeine and taurine have a null or negative effect on sprint performance. J Strength Cond Res. 2017;1

  62. Seifert SM, Seifert SA, Schaechter JL, Bronstein AC, Benson BE, Hershorin ER, et al. An analysis of energy-drink toxicity in the National Poison Data System. Clin Toxicol. 2013;51(7):566–74.

    Article  Google Scholar 

  63. Valle MTC, Couto-Pereira NS, Lampert C, Arcego DM, Toniazzo AP, Limberger RP, et al. Energy drinks and their component modulate attention, memory,and antioxidant defences in rats. Eur J Nutr. 2017;

  64. Vivekanandarajah A, Ni S, Waked A. Acute hepatitis in a woman following excessive ingestion of an energy drink: a case report. J Med Case Rep. 2011;5:227.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Huang B, Kunkel D, Kabany M El. Acute liver failure following one year of daily consumption of a sugar-free energy drink. ACG Case Reports J 2014;1(4):214–216.

  66. Harb JN, Taylor ZA, Khullar V, Sattari M. Rare cause of acute hepatitis: a common energy drink. BMJ Case Rep. 2016;2016:1–4.

    Google Scholar 

  67. Astorino TA, Matera AJ, Basinger J, Evans M, Schurman T, Marquez R. Effects of red bull energy drink on repeated sprint performance in women athletes. Amino Acids. 2012;42(5):1803–8.

    Article  PubMed  CAS  Google Scholar 

  68. Del Coso J, Muñoz-Fernández VE, Muñoz G, Fernández-Elías VE, Ortega JF, Hamouti N, et al. Effects of a caffeine-containing energy drink on simulated soccer performance. PLoS One. 2012;7(2):e31380.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  69. Salinero JJ, Lara B, Abian-Vicen J, Gonzalez-Mill NC, Areces F, Gallo-Salazar C, et al. The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes. Br J Nutr. 2014;112(9):1494–502.

    Article  PubMed  CAS  Google Scholar 

  70. Smit HJ, Cotton JR, Hughes SC, Rogers PJ. Mood and cognitive performance effects of “energy” drink constituents: caffeine, glucose and carbonation. Nutr Neurosci. 2004;7(3):127–39.

    Article  PubMed  CAS  Google Scholar 

  71. • Ali F, Rehman H, Babayan Z, Stapleton D, Joshi DD. Energy drinks and their adverse health effects: a systematic review of the current evidence. Postgrad Med. 2015;127(3):308–22. This review highlights the adverse health effects of energy drinks.

  72. Higgins JP, Babu K, Deuster PA, Shearer J. Energy drinks: a contemporary issues paper. Curr Sports Med Rep. 2018;17(2):65–72.

    Article  PubMed  Google Scholar 

  73. Gunja N, Brown JA. Energy drinks: health risks and toxicity. Med J Aust. 2012;196(1):46–9.

    Article  PubMed  Google Scholar 

  74. Marmorstein NR. Interactions between energy drink consumption and sleep problems: associations with alcohol use among young adolescents. J Caffeine Res. 2017;7(3):111–6.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  75. Fletcher EA, Lacey CS, Aaron M, Kolasa M, Occiano A, Shah SA. Randomized controlled trial of high-volume energy drink versus caffeine consumption on ECG and hemodynamic parameters. J Am Heart Assoc. 2017;6(5):1–8.

    Article  Google Scholar 

  76. Gray B, Ingles J, Medi C, Driscoll T, Semsarian C. Cardiovascular effects of energy drinks in familial long QT syndrome: a randomized cross-over study. Int J Cardiol. 2017;231:150–4.

    Article  PubMed  Google Scholar 

  77. Higgins JP, Yang B, Herrin NE, Yarlagadda S, Le GT, Ortiz BL, et al. Consumption of energy beverage is associated with attenuation of arterial endothelial flow-mediated dilatation. World J Cardiol. 2017;9(2):162.

    Article  PubMed  PubMed Central  Google Scholar 

  78. Pagano CW, Wu M, Wu L. Acute visual loss and intraretinal hemorrhages associated to energy drink consumption. Int Ophthalmol. 2017;37(6):1349–51.

    Article  PubMed  Google Scholar 

  79. Worthley MI, Prabhu A, De Sciscio P, Schultz C, Sanders P, Willoughby SR. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med. 2010;123(2):184–7.

    Article  PubMed  CAS  Google Scholar 

  80. Williams RD, Housman JM, Odum M, Rivera AE. Energy drink use linked to high-sugar beverage intake and BMI among teens. Am J Health Behav. 2017;41(3):259–65.

    Article  PubMed  Google Scholar 

  81. Richards G, Smith APA. Review of energy drinks and mental health, with a focus on stress, anxiety and Depression. J Caffeine Res. 2016;6(2):49–63.

    Article  PubMed  PubMed Central  Google Scholar 

  82. Kim SY, Sim S, Choi HG. High stress, lack of sleep, low school performance, and suicide attempts are associated with high energy drink intake in adolescents. PLoS One. 2017;12(11):1–12.

    Google Scholar 

  83. Utter J, Denny S, Teevale T, Sheridan J. Energy drink consumption among New Zealand adolescents: associations with mental health, health risk behaviours and body size. J Paediatr Child Health. 2018;54(3):279–83.

    Article  PubMed  Google Scholar 

  84. Jeffers AJ, Hill KEV, Benotsch EG. Energy drinks, weight loss and disordered eating behaviors. J Am Coll Heal. 2014;62(5):336–42.

    Article  Google Scholar 

  85. Arria AM, Caldeira KM, Bugbee BA, Vincent KB, O’Grady KE. Trajectories of energy drink consumption and subsequent drug use during young adulthood. Drug Alcohol Depend. 2017;179:424–32.

    Article  PubMed  PubMed Central  Google Scholar 

  86. Picard-Masson M, Loslier J, Paquin P, Bertrand K. Consumption of energy drinks among Québec college students. Can J Public Health. 2017;107(6):e514–9.

    Article  PubMed  Google Scholar 

  87. • Leal WE, Jackson DB. Energy drinks and escalation in drug use severity: An emergent hazard to adolescent health. Prev Med (Baltim). 2018;111:391–6. This study reviews the relationship between energy drinks consumption and drug use.

  88. Polak K, Dillon P, Koch JR, Miller WG, Thacker L, Svikis D. Energy drink use is associated with alcohol and substance use in eighth, tenth, and twelfth graders. Prev Med Reports. 2016;4:381–4.

    Article  Google Scholar 

  89. Accessed on 5.15.2018 [Internet]. Available from:

  90. Miyake ER, Marmorstein NR. Energy drink consumption and later alcohol use among early adolescents. Addict Behav. 2015;43:60–5.

    Article  PubMed  Google Scholar 

  91. Holubcikova J, Kolarcik P, Madarasova Geckova A, Joppova E, van Dijk JP, Reijneveld SA. Young adolescents who combine alcohol and energy drinks have a higher risk of reporting negative behavioural outcomes. Int J Public Health. 2017;62(3):379–86.

    Article  PubMed  Google Scholar 

  92. Berger L, Fendrich M, Fuhrmann D. Alcohol mixed with energy drinks: are there associated negative consequences beyond hazardous drinking in college students? Addict Behav. 2013;38(9):2428–32.

    Article  PubMed  PubMed Central  Google Scholar 

  93. Howland J, Rohsenow DJ. Risks of energy drinks mixed with alcohol. JAMA - J Am Med Assoc. 2013;309(3):245–6.

    Article  CAS  Google Scholar 

  94. Accessed on 5.15.2018 [Internet]. Available from:

  95. Accessed on 5.15.2018 [Internet]. Available from:

  96. Marczinski CA, Fillmore MT, Maloney SF, Stamates AL. Faster self-paced rate of drinking for alcohol mixed with energy drinks versus alcohol alone. Psychol Addict Behav. 2017;31(2):154–61.

    Article  PubMed  Google Scholar 

  97. Mosca A, Della Corte C, Sartorelli MR, Ferretti F, Nicita F, Vania A, et al. Beverage consumption and paediatric NAFLD. Eat Weight Disord. 2016;21(4):581–8.

    Article  PubMed  Google Scholar 

  98. Reis R, Charehsaz M, Sipahi H, Ekici AID, Macit Ç, Akkaya H, et al. Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol. J Food Sci. 2017;82(4):1037–43.

    Article  PubMed  CAS  Google Scholar 

  99. McCrory C, White CM, Bowman C, Fenton N, Reid JL, Hammond D. Perceptions and Knowledge of caffeinated energy drinks: results of focus groups with Canadian youth. J Nutr Educ Behav 2017;49(4):304–311.e6.

  100. Xiang N, Wethington H, Onufrak S, Belay B. Characteristics of US health care providers who counsel adolescents on sports and energy drink consumption. Int J Pediatr. 2014;2014:1–10.

    Article  Google Scholar 

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Correspondence to Senthilkumar Sankararaman.

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Conflict of Interest

Senthilkumar Sankararaman is supported by a sponsored fellowship program with the Nestlé Nutrition Institute.

Wahid Syed declares that he has no conflict of interest.

Valentina Medici declares that she has no conflict of interest.

Thomas J. Sferra declares that he has no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Gastroenterology, Critical Care, and Lifestyle Medicine

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Sankararaman, S., Syed, W., Medici, V. et al. Impact of Energy Drinks on Health and Well-being. Curr Nutr Rep 7, 121–130 (2018).

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  • Energy drinks
  • Energy shots
  • Supplements
  • Caffeine
  • Taurine