The Role of Sleep Duration on Energy Balance: an Update
The relation between sleep duration and weight status is well established, and growing evidence suggests this relation is causal. However, the mechanisms underlying the sleep/obesity relation remain controversial. We have previously reviewed the evidence relating sleep restriction to energy balance regulation, uncovering much discrepancy in physiological/hormonal explanations. Herein, we perform an in-depth assessment of the evidence, published since 2012, of the impact of sleep restriction on energy balance regulation. Increased energy intakes as a result of sleep curtailment are consistently observed, but effects on its hormonal regulators are debatable. Future studies should continue to enroll women, perform hormonal measurements under controlled, weight maintenance feeding conditions, and lengthen the intervention period beyond five nights to elucidate the mechanism linking sleep and obesity.
KeywordsSleep Food intake Ghrelin Leptin Sleep debt Partial sleep restriction Total sleep deprivation Sleep extension
Dr. St-Onge has received funding from the National Institutes of Health (1R56HL119945) and the American Heart Association (16SFRN27950012) for this work.
Compliance with Ethical Standards
Conflict of Interest
Marie-Pierre St-Onge, Ashlee Bormes, and Ismel Salazar declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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