Application of Metabolomics to Assess Effects of Controlled Dietary Interventions

Abstract

The utilization of metabolomics technologies as part of nutritional investigations has rapidly increased during the last few years. The application of both nuclear magnetic resonance (NMR) and mass spectrometry (MS) based technologies is providing wide information on both the diet-derived compounds and their metabolites related to specific foods or diets, as well as aiding the in-depth exploration of the endogenous metabolic phenomena related to different diets. The analytical accuracy nowadays enables examination of metabolite composition of both urine and plasma to very high molecular detail even at low concentrations, and will be focal in gaining wider metabolic understanding of the relationship between eating habits and maintenance of good health.

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Correspondence to Kati Hanhineva.

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Hanhineva, K. Application of Metabolomics to Assess Effects of Controlled Dietary Interventions. Curr Nutr Rep 4, 365–376 (2015). https://doi.org/10.1007/s13668-015-0148-0

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Keywords

  • Metabolomics
  • Metabolite profiling
  • Nutrition
  • Intervention
  • Clinical trial
  • Food and health
  • Diet and health
  • Healthy diet
  • Phytochemical
  • Mass spectrometry
  • LC-MS
  • GC-MS
  • Nuclear magnetic resonance
  • NMR