Air Travel-Related Spontaneous Pneumothorax in Diffuse Cystic Lung Diseases

Pleural Diseases and Mesothelioma (G Lee, Section Editor)
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Abstract

Purpose of Review

Spontaneous pneumothorax (SP) is a common manifestation of patients with diffuse cystic lung diseases (DCLDs) such as lymphangioleiomyomatosis (LAM), pulmonary Langerhans cell histiocytosis (PLCH), and Birt-Hogg-Dubé syndrome (BHD). Air travel may pose an additional risk for the development of SP. Here, we summarize the literature pertaining to air travel-related SP in DCLDs in order to assist patients and clinicians in appropriate decision-making with regard to air travel.

Recent Findings

Several recent studies have estimated that the per-flight risk of SP in patients with DCLDs is approximately 1%, with disease-specific risk estimates of 1.1–2.6% in LAM, 0–0.63% in BHD, and 0.37% in PLCH.

Summary

In general, it should be safe for most patients with DCLDs to undertake air travel. Patients should be counseled to seek medical attention and not board the airplane in the presence of sudden/new onset chest pain and/or dyspnea prior to boarding the plane.

Keywords

Air travel Birt-Hogg-Dubé syndrome Diffuse cystic lung disease Lymphangioleiomyomatosis Pulmonary Langerhans cell histiocytosis Spontaneous pneumothorax 

Notes

Compliance with Ethical Standards

Conflict of Interest

Nishant Gupta and Nikolai Wajda declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Supplementary material

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ESM 1 (WAV 23207 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Pulmonary, Critical Care, and Sleep MedicineUniversity of CincinnatiCincinnatiUSA

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