Abstract
Three new jatropholane-type diterpenoids, jatropholones C-E (1–3), along with seven other known compounds, including sikkimenoid B (4), jatrophaldehyde (5), epi-jatrophaldehyde (6), epi-jatrophol (7), jatrophol (8), jatropholone A (9), and jatropholone B (10), were isolated from the roots of a natural cultivar of Jatropha curcas (J. curcas cv. Multiflorum CY Yang). The structural elucidations of 1–3 were accomplished by extensive NMR analysis. Compounds 4, 6, and 8 demonstrated inhibition activity against the microorganisms with the MIC values from 0.10 to 0.18 mg/mL.
![](http://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs13659-013-0031-x/MediaObjects/13659_2013_31_Article_Fig1_HTML.gif)
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
The editor committee of Flora Repubulicae Popularis Sinicae, the Chinese academy of sciences. Euphorbiaceae (II) Subfam. Acalyphoideae Subfam. Crotonoideae. Science Press: Beijing, China, 1996; 44: 147–149.
http://www.xtbg.cas.cn/xwzx/kydt/201112/t20111223_3416898.html
Zhang, X. P.; Zhang, M. L.; Su, X. H.; Huo, C. H.; Gu, Y. C.; Shi, Q. W. Chem. Biodiver. 2009, 6, 2166–2183.
Sabandar, C. W.; Ahmat, N.; Jaafar, F. M.; Sahidin, I. Phytochemistry2012, 85, 7–29.
Pertino, M.; Schmeda-Hirschmann, G.; Rodriguez, J. A.; Theoduloz, C. Planta Med. 2007, 73, 1095–1100.
Theoduloz, C.; Rodriguez, J. A.; Pertino, M. Planta Med. 2009, 75, 1520–1522.
Goncalves de Moraes, V. L.; Rumjanek, V. M.; Calixto, J. B. Eur. J. Pharmacol. 1996, 312, 333–339.
Sutthivaiyakit, S.; Mongkolvisut, W.; Prabpai, S.; Kongsaeree, P. J. Nat. Prod. 2009, 72, 2024–2027.
Taylor, M. D.; Smith III, A. B.; Furst, G. T.; Gunasekara, S. P.; Bevelle, C. A.; Cordell, G. A.; Farnsworth, N. R.; Kupchan, S. M.; Uchida, H.; Branfman, A. R.; Dailey, R. G.; Sneden, A. T. J. Am. Chem. Soc. 1983, 105, 3177–3183.
Kupchan, S. M.; Sigel, C. W.; Matz, M. J.; Saenz Renauld, J. A.; Haltiwanger, R. C.; Bryan, R. F. J. Am. Chem. Soc. 1970, 92, 4476–4477.
Wang, X. C.; Zheng, Z. P.; Gan, X. W.; Hu, Li. H. Org. Lett. 2009, 11, 5522–5524.
http://www.xtbg.ac.cn/xwzx/kydt/201112/t20111223_3416898.html
Liu, J. Q.; Yang, Y. F.; Wang, C. F.; Li, Y.; Qiu, M. H. Tetrahedron2012, 68, 972–976.
Yang, Y. F.; Liu, J. Q.; Li, X. Y.; Liu, E. Q.; Li, Z. R.; Qiu, M. H. Chin. Sci. Bull. 2013, 58, 1–5.
Yang, D. S.; Zhang, Y. L.; Peng, W. B.; Wang, L. Y.; Li, Z. L.; Wang, X.; Liu, K. C.; Yang, Y. P.; Li, H. L.; Li, X. L. J. Nat. Prod. 2013, 76, 265–269.
Zhang, X. Q.; Li, F.; Zhao, Z. G.; Liu, X. L.; Tang, Y. X.; Wang, M. K. Phytochem. Lett. 2012, 5, 721–724.
Chen, M.; Hou, L.; Zhang, G. Zhiwu Xuebao1988, 30, 308–311.
Purushothaman, K. K.; Chandrasekharan, S.; Cameron, A. F.; Connolly, J. D.; Labbe, C.; Maltz, A.; Rycroft, D. S. Tetrahedron Lett. 1979, 11, 979–980
Kong, L.; Min, Z.; Shi, J. Zhiwu Xuebao1996, 38, 161–166.
Miyazawa, M.; Uemura, T.; Kameoka, H. Phytochemistry1994, 37, 1027–1030.
National Committee for Clinical Laboratory Standards, 2003. Methods for Dilution Antimicrobial Susceptibility Test for Bacteria that Grow aerobically, 5th ed. Approved standard document M7-A6, Wayne, PA.
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is published with open access at Springerlink.com
Electronic supplementary material
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Yang, YF., Liu, JQ., Shi, L. et al. New jatropholane-type diterpenes from Jatropha curcas cv. Multiflorum CY Yang. Nat. Prod. Bioprospect. 3, 99–102 (2013). https://doi.org/10.1007/s13659-013-0031-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13659-013-0031-x