Abstract
Dendrowardol C (1)—a novel sesquiterpenoid, with an unprecedented 4/5/6/6 tetracyclic carbon backbone, together with two known cyclopacamphane-type sesquiterpenoids; dendronobilin I (2) and dendrobane A (3) were isolated from the stems of Dendrobium wardianum Warner. The structure of 1 was established on the basis of spectroscopic data and the absolute configuration was determined by single-crystal X-ray diffraction crystallography. The hypothetical biosynthetic pathway of 1 was postulated. Compound 1 showed no cytotoxic activity against human tumor cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480.
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Fan, WW., Xu, FQ., Dong, FW. et al. Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum Warner. Nat. Prod. Bioprospect. 3, 89–92 (2013). https://doi.org/10.1007/s13659-013-0024-9
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DOI: https://doi.org/10.1007/s13659-013-0024-9