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Norsesquiterpenoids from the leaves of Croton tiglium

Natural Products and Bioprospecting volume 1, pages134–137(2011)Cite this article

Abstract

Two new compounds, badounoids A (1) and B (2), together with 13 known norsesquiterpenes, were isolated from the leaves of Croton tiglium L. The structures of the new compounds were established by means of spectroscopic methods. The absolute configuration of badounoid B was determined by single-crystal X-ray diffraction analysis. All the known compounds were isolated from Croton plants for the first time which added a new chemical facet for this genus. The selected compounds were evaluated for their cytostatic activity against several cancer cell lines. None of them was found to be active.

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Affiliations

  1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
    • Wei Bu
    • , Yan-Ni Shi
    • , Yong-Ming Yan
    • , Qing Lu
    • , Yan Li
    •  & Yong-Xian Cheng
  2. Graduate University of Chinese Academy of Sciences, Beijing, 100049, China
    • Yan-Ni Shi
  3. Faculty of Pharmacy, Dali University, Dali, 671000, China
    • Wei Bu
    •  & Guang-Ming Liu
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  1. Wei Bu
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  2. Yan-Ni Shi
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Correspondence to Yan Li or Yong-Xian Cheng.

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These authors contributed equally to this work.

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Bu, W., Shi, Y., Yan, Y. et al. Norsesquiterpenoids from the leaves of Croton tiglium. Nat. Prod. Bioprospect. 1, 134–137 (2011). https://doi.org/10.1007/s13659-011-0035-3

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Keywords

  • Croton tiglium
  • badounoid
  • norsesquiterpenoid
  • cytostatic activity