Skip to main content

Advertisement

SpringerLink
Go to cart
  1. Home
  2. Natural Products and Bioprospecting
  3. Article
Euglobal-IIIa, a novel acylphloroglucinol-sesquiterpene derivative from Eucalyptus robusta: absolute structure and cytotoxicity
Download PDF
Your article has downloaded

Similar articles being viewed by others

Slider with three articles shown per slide. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide.

A New Ursane-Type Triterpenoid from the Leaves of Rhododendron dauricum with Cytotoxic Activity

27 March 2021

Chao Ye, Mei Jin, … Gao Li

A New Triterpene and a New Phloroglucinol Derivative from the Aerial Parts of Pogostemon auricularius

01 September 2019

Duc Viet Ho, Linh Thuy Thi Tran, … Ain Raal

Isolation of Sesquiterpene Lactones and the Antioxidant and Anticancer Activities of Crude Extracts from Cyanthillium cinereum

01 January 2022

J. Dharani & S. Ravi

New Benzophenone and Bioactive Constituents from Hypericum nagasawae

24 September 2022

Fu-Sen Wu, I-Chou Wang, … Jih-Jung Chen

A New Acenaphthylene and Bioactive Constituents of Salvia arisanensis

18 November 2021

Chien-Ming Huang, Chun-Hao Chang, … Jih-Jung Chen

A New Benzophenone and Bioactive Constituents of Hypericum nokoense

14 July 2021

Fu-Sen Wu, Ching-Ju Hung, … Jih-Jung Chen

Chemical Constituents from Acanthopanax senticosus and Their Cytotoxic Activities

01 July 2022

Ying-Ying Wei, Peng Han, … Fan Li

Triterpenoids from Phytolacca acinosa

15 March 2019

Xiao-Pan Ma, Hua-Yong Lou, … Wei-Dong Pan

Cytotoxic diterpenoid alkaloid from Aconitum japonicum subsp. subcuneatum

25 July 2019

Hiroshi Yamashita, Mai Miyao, … Koji Wada

Download PDF
  • Short Communication
  • Open Access
  • Published: 26 October 2011

Euglobal-IIIa, a novel acylphloroglucinol-sesquiterpene derivative from Eucalyptus robusta: absolute structure and cytotoxicity

  • Li-Yan Peng1,
  • Juan He1,
  • Gang Xu1,
  • Xing-De Wu1,
  • Liao-Bin Dong1,
  • Xiu Gao1,
  • Xiao Cheng1,
  • Jia Su1,
  • Yan Li1 &
  • …
  • Qin-Shi Zhao1 

Natural Products and Bioprospecting volume 1, pages 101–103 (2011)Cite this article

  • 947 Accesses

  • 11 Citations

  • Metrics details

Abstract

Euglobal-IIIa (1), a novel acylphloroglucinol-sesquiterpene derivative, and a known analogue, have been isolated from leaves of Eucalyptus robusta. The structures was elucidated by extensive spectroscopic data and by comparison with data reported in literature, while the absolute configuration of 1 was determined by the X-ray diffraction analysis. Compound 1 exhibited comparable cytotoxicity with that of cisplatin against five human cancer cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480 with IC50 values of 15.7, 15.5, 17.6, 14.3, and 21.8 µM, respectively.

Download to read the full article text

Working on a manuscript?

Avoid the common mistakes

References

  1. Sawada, T.; Kozuka, M.; Komiya, T.; Amano, T.; Goto, M. Chem. Pharm. Bull.1980, 28, 2546–2548.

    Article  CAS  Google Scholar 

  2. Amano, T.; Komiya, T.; Hori, M.; Goto, M.; Kozuka, M.; Sawada, T. J. Chromatogr.1981, 208, 347–355.

    Article  CAS  Google Scholar 

  3. Kokumai, M.; Konoshima, T.; Kozuka, M.; Haruna, M.; Ito, K. J. Nat. Prod.1991, 54, 1082–1086.

    Article  CAS  Google Scholar 

  4. Takasaki, M.; Konoshima, T.; Kozuka, M.; Haruna, M.; Ito, K.; Crow, W. D.; Paton, D. M. Chem. Pharm. Bull.1994, 42, 2113–2116.

    Article  PubMed  CAS  Google Scholar 

  5. Cheng, Q.; Snyder, J. K. J. Org. Chem.1988, 53, 4562–4567.

    Article  CAS  Google Scholar 

  6. Takasaki, M.; Konoshima, T.; Kozuka, M.; Haruna, M.; Ito, K. Nat. Med. (Tokyo)1997, 51, 486–490.

    CAS  Google Scholar 

  7. Takasaki, M.; Konoshima, T.; Kozuka, M.; Haruna, M.; Ito, K.; Yoshida, S. Chem. Pharm. Bull.1994, 42, 2177–2179.

    Article  CAS  Google Scholar 

  8. Takasaki, M.; Konoshima, T.; Fujitani, K.; Yoshida, S.; Nishimura, H.; Tokuda, H.; Nishino, H.; Iwashima, A.; Kozuka, M. Chem. Pharm. Bull.1990, 38, 2737–2739.

    Article  PubMed  CAS  Google Scholar 

  9. Takasaki, M.; Konoshima, T.; Kozuka, M.; Tokuda, H. Biol. Pharm. Bull.1995, 18, 435–438.

    Article  PubMed  CAS  Google Scholar 

  10. Takasaki, M.; Konoshima, T.; Etoh, H.; Pal Singh, I.; Tokuda, H.; Nishino, H. Cancer Lett.2000, 155, 61–65.

    Article  PubMed  CAS  Google Scholar 

  11. Bharate, S. B.; Bhutani, K. K.; Khan, S. I.; Tekwani, B. L.; Jacob, M. R.; Khan, I. A.; Singh, I. P. Bioorg. Med. Chem.2006, 14, 1750–1760.

    Article  PubMed  CAS  Google Scholar 

  12. Kozuka, M.; Sawada, T.; Mizuta, E.; Kasahara, F.; Amano, T.; Komiya, T.; Goto, M. Chem. Pharm. Bull.1982, 30, 1964–1973.

    Article  CAS  Google Scholar 

  13. Satoh, H.; Etoh, H.; Watanabe, N.; Kawagishi, H.; Arai, K.; Ina, K. Chem. Lett.1992, 21, 1917–1920.

    Article  Google Scholar 

  14. Fu, H. Z.; Luo, Y. M.; Li, C. J.; Yang, J. Z.; Zhang, D. M. Org. Lett.2010, 12, 656–659.

    Article  PubMed  CAS  Google Scholar 

  15. Mosmann, T. J. Immunol. Methods1983, 65, 55–63.

    Article  PubMed  CAS  Google Scholar 

  16. Reed, L. J.; Muench, H. Am. J. Hyg.1938, 27, 493–497.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China

    Li-Yan Peng, Juan He, Gang Xu, Xing-De Wu, Liao-Bin Dong, Xiu Gao, Xiao Cheng, Jia Su, Yan Li & Qin-Shi Zhao

Authors
  1. Li-Yan Peng
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Juan He
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gang Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Xing-De Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Liao-Bin Dong
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Xiu Gao
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Xiao Cheng
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Jia Su
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Yan Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Qin-Shi Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Qin-Shi Zhao.

Additional information

This article is published with open access at Springerlink.com

Electronic supplementary material

Supplementary material, approximately 22.3 KB.

Rights and permissions

Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and Permissions

About this article

Cite this article

Peng, LY., He, J., Xu, G. et al. Euglobal-IIIa, a novel acylphloroglucinol-sesquiterpene derivative from Eucalyptus robusta: absolute structure and cytotoxicity. Nat. Prod. Bioprospect. 1, 101–103 (2011). https://doi.org/10.1007/s13659-011-0021-9

Download citation

  • Received: 25 September 2011

  • Accepted: 11 October 2011

  • Published: 26 October 2011

  • Issue Date: October 2011

  • DOI: https://doi.org/10.1007/s13659-011-0021-9

Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

Keywords

  • Eucalyptus robusta
  • acylphloroglucinol-sesquiterpene
  • absolute structure
  • cytotoxicity
Download PDF

Working on a manuscript?

Avoid the common mistakes

Advertisement

Over 10 million scientific documents at your fingertips

Switch Edition
  • Academic Edition
  • Corporate Edition
  • Home
  • Impressum
  • Legal information
  • Privacy statement
  • Your US state privacy rights
  • How we use cookies
  • Your privacy choices/Manage cookies
  • Accessibility
  • FAQ
  • Contact us
  • Affiliate program

Not affiliated

Springer Nature

© 2023 Springer Nature Switzerland AG. Part of Springer Nature.