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The GC–MS analysis of the diethylether and ethylacetate fraction of the peel of Solanum incanum and the study of their antibacterial activity

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Abstract

The diethyl ether and ethyl acetate fractions of the peel of the fruit of Solanum incanum. (S. incanum) were analyzed using gas chromatography-mass spectrometry (GC–MS). 105 compounds were identified in the diethyl ether fraction and 75 compounds were identified in ethyl acetate fraction. Among them, 5 compounds were analyzed by fragmentation pattern, discussed, and compared with NIST database. The antibacterial screening was also conducted for bothdiethyl ether and ethyl acetate fractions of the fruit peel of S.incanum using four pathogens, two Gram-positive bacteria Staphylococcus aureus (S. aureus) and Streptococcus pyogenes (S. pyogenes) and two Gram negative bacteria Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumonia), at various concentrations (250, 500, 750 and 1000 μg/ml). The diethyl ether and ethyl acetate fractions of the peel of S. incanum exhibited activity against E. coli and K. pneumonia at 1000 μg/ml concentration.

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Acknowledgements

The authors thank the management of Wollega University and the Ministry of Science and Higher Education, Ethiopia for providing the required facilities to carry out this research work.

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Authors and Affiliations

  1. Department of Chemistry, College of Natural and Computational Sciences, Wollega University, Nekemte, Ethiopia

    Yesudass Dominic Ravichandran & Mequanint Molla Yetayih

  2. Department of Science and Humanities, Karpagam College of Engineering, Coimbatore, India

    Yesudass Dominic Ravichandran

  3. Department of Chemistry, College of Natural and Computational Sciences, Debre Tabor, University, Debre Tabor, Ethiopia

    Mequanint Molla Yetayih

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  1. Yesudass Dominic Ravichandran
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Correspondence to Yesudass Dominic Ravichandran.

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This article does not contain any studies involving animals performed by any of the authors. This article does not contain any studies involving human participants performed by any of the authors.

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Yesudass Dominic Ravichandran has no conflict of interest. Mequanint Yetayih has no conflict of interest.

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Ravichandran, Y.D., Yetayih, M.M. The GC–MS analysis of the diethylether and ethylacetate fraction of the peel of Solanum incanum and the study of their antibacterial activity. ADV TRADIT MED (ADTM) 22, 809–821 (2022). https://doi.org/10.1007/s13596-021-00623-1

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  • DOI: https://doi.org/10.1007/s13596-021-00623-1

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