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Evaluation of hair growth properties of Topical Kombucha tea extracts


Consuming functional foods and drinks such as kombucha tea is believed to give many beneficial effects for promoting immunity and preventing cancer. The fermented tea with sugar and symbiotic culture of yeast and bacteria is also useful in the topical application for hair re-growth. This study aims to investigate hair re-growth properties of kombucha black tea and chamomile with and without methylsulfonylmethane. Treatments were applied topically to denuded Balb/c mice and observed for hair growth initiation time, density and length in 15 and 30 days in addition to microbiological identification of the main yeast and bacteria. Results showed significantly better hair density and length in groups treated with kombucha black tea with and without MSM, followed by kombucha chamomile tea with and without MSM respectively. In addition, it has been found that MSM promotes hair growth significantly when combined with kombucha ferments. Microbiological analysis indicated the presence of Zygosaccharomyces bailii and Acetobacter genus in the tea broth. Black tea kombucha with MSM can be used as a natural alternative therapy for hair fall and a cost-effective treatment with fewer side effects compared to the synthetic drugs.

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Fig. 1

adopted from six mice in the treated mice group on day 15 and 30. G7 mice treated by kombucha/ black tea with MSM which have the best hair density scores followed by kombucha/ black tea, kombucha chamomile tea with MSM, kombucha chamomile tea, and minoxidil. Results are means ± SEM from six mice in each group, on day 15 and day 30. *p < 0.05, ** p < 0.001, *** p < 0.0001 (p value was calculated compared to negative control group)

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This work was funded by Al-Isra University, Amman, Jordan.


The project was fully funded by Al-Isra university, Amman, Jordan, under grant No. 2019/2018/17-174

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Corresponding author

Correspondence to Manal Mamdouh Al-Najdawi.

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Ethical statement

All animal handling in the present study were conducted according to the guidelines of Institutional Animal Care and Use Committee (IACUC) and the research ethics committee of the faculty of pharmacy, Isra University has approved it under approval No. 55-5/2019-2020.

Conflicts of interest

Mohammed Ayad Alboreadi has no conflict of interest. Manal Mamdouh Al‑Najdawi has no conflict of interest. Qais Bashir Jarrar has no conflict of interest. Said Moshawih has no conflict of interest.

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Alboreadi, M.A., Al-Najdawi, M.M., Jarrar, Q.B. et al. Evaluation of hair growth properties of Topical Kombucha tea extracts. ADV TRADIT MED (ADTM) (2021).

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  • Kumbocha
  • Black tea
  • Chamomile
  • Hair growth
  • Zygosaccharomyces
  • Acetobacter