Skip to main content
SpringerLink
Log in

CTLA-4 and ovarian cancer residual tumors: the dark side of debulking surgery

  • Letter to the Editor
  • Published:
Human Cell Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Data availability

Not applicable.

References

  1. Bivona TG, Doebele RC. A framework for understanding and targeting residual disease in oncogene-driven solid cancers. Nat Med. 2016;22:472–8. https://doi.org/10.1038/nm.4091.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. El-Arabey AA, Abdalla M, Abd-Allah AR. GATA3 and stemness of high-grade serous ovarian carcinoma: novel hope for the deadliest type of ovarian cancer. Hum Cell. 2020;33:904–6. https://doi.org/10.1007/s13577-020-00368-0.

    Article  PubMed  Google Scholar 

  3. Polterauer S, Vergote I, Concin N, Braicu I, Chekerov R, Mahner S, et al. Prognostic value of residual tumor size in patients with epithelial ovarian cancer FIGO stages IIA-IV: analysis of the OVCAD data. Int J Gynecol Cancer. 2012;22:380–5. https://doi.org/10.1097/IGC.0b013e31823de6ae.

    Article  PubMed  Google Scholar 

  4. El-Arabey AA, Abdalla M. The role of GATA3 in the metastasis of triple-negative breast cancer and high-grade serous ovarian cancer. Hum Cell. 2022;35:1298–300. https://doi.org/10.1007/s13577-022-00706-4.

    Article  CAS  PubMed  Google Scholar 

  5. Lee YJ, Kim D, Shim JE, Bae S-J, Jung Y-J, Kim S, et al. Genomic profiling of the residual disease of advanced high-grade serous ovarian cancer after neoadjuvant chemotherapy. Int J Cancer. 2020;146:1851–61. https://doi.org/10.1002/ijc.32729.

    Article  CAS  PubMed  Google Scholar 

  6. Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12:252–64. https://doi.org/10.1038/nrc3239.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Koch A, Jeschke J, van Criekinge W, van Engeland M, de Meyer T. MEXPRESS update 2019. Nucleic Acids Res. 2019;47:W561–5. https://doi.org/10.1093/nar/gkz445.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan, 250022, Shandong, China

    Mohnad Abdalla & Zhongtao Gai

  2. Shandong Provincial Clinical Research Center for Children’s Health and Disease, Jinan, 250022, Shandong, China

    Mohnad Abdalla & Zhongtao Gai

  3. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, 11751, Egypt

    Amr Ahmed El-Arabey

Authors
  1. Mohnad Abdalla
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Amr Ahmed El-Arabey
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhongtao Gai
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Conception or design of the work: AAE-A and ZG; drafting the article: MA. All authors critically reviewed the manuscript and approved the final version.

Corresponding authors

Correspondence to Amr Ahmed El-Arabey or Zhongtao Gai.

Ethics declarations

Conflict of interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdalla, M., El-Arabey, A.A. & Gai, Z. CTLA-4 and ovarian cancer residual tumors: the dark side of debulking surgery. Human Cell 36, 2281–2283 (2023). https://doi.org/10.1007/s13577-023-00976-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13577-023-00976-6

Keywords

Search

Navigation