Skip to main content
SpringerLink
Log in

Expression of miR-132 in Down syndrome subjects

  • Letter to the Editor
  • Published:
Human Cell Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Roizen NJ, Patterson D. Down’s syndrome. Lancet. 2003;361:1281–9.

    Article  PubMed  Google Scholar 

  2. Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci. 2006;29:77–103.

    Article  PubMed  CAS  Google Scholar 

  3. Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet. 2008;9:102–14.

    Article  PubMed  CAS  Google Scholar 

  4. Eacker SM, Dawson TM, Dawson VL. Understanding microRNAs in neurodegeneration. Nat Rev Neurosci. 2009;10:837–41.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Elton TS, Sansom SE, Martin MM. Trisomy21 gene dosage overexpression of miRNAs results in the haploinsuffciency of specifc target proteins. RNA Biol. 2010;7:540–47.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Lin H, Sui W, Li W, Tan Q, Chen J, Lin X, Guo H, Ou M, Xue W, Zhang R, Dai Y. Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal Down syndrome. Mol Med Rep. 2016;14:4109–118.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Hernandez-Rapp J, Smith PY, Filali M, Goupil C, Planel E, Magill ST, Goodman RH. Hébert SS.Memory formation and retention are affected in adult miR-132/212 knockout mice. Behav. Brain Res. 2015;287:15–26.

    CAS  Google Scholar 

  8. Hansen KF, Sakamoto K, Wayman GA, Impey S, Obrietan K. Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory. PLoS One. 2010;29:e15497.

    Article  CAS  Google Scholar 

  9. Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpGbinding protein 2. Nat Genet. 1999;23:185–88.

    Article  PubMed  CAS  Google Scholar 

  10. Smrt RD, Eaves-Egenes J, Barkho BZ, et al. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol Dis. 2007;27:77–89.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Oasi Research Institute-IRCCS, Troina, Italy

    Michele Salemi, Concetta Barone, Maria Grazia Salluzzo, Mariaconcetta Giambirtone & Corrado Romano

  2. Department of Transfusional Medicine, General Hospital of Treviso, Treviso, Italy

    Federico Ridolfo

Authors
  1. Michele Salemi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Concetta Barone
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Maria Grazia Salluzzo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mariaconcetta Giambirtone
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Federico Ridolfo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Corrado Romano
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Michele Salemi.

Ethics declarations

Conflict of interest

The authors report no declarations of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Salemi, M., Barone, C., Salluzzo, M.G. et al. Expression of miR-132 in Down syndrome subjects. Human Cell 31, 268–270 (2018). https://doi.org/10.1007/s13577-018-0209-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13577-018-0209-y

Keywords

Search

Navigation