Biosynthesis, characterization and antibacterial activity of silver nanoparticles by aqueous Annona squamosa L. leaf extract at room temperature
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Silver nanoparticles (AgNPs) have gained great interest in nanotechnology, biotechnology and medicine. The green synthesis of nanoparticles has received an increasing attention because of it’s maximize efficiency and minimize health and environmental hazards as compared to other conventional chemical synthesis. In this study, we reported biosynthesis of AgNPs by aqueous Annona squamosa L. leaf extract and its characterization by UV-visible spectroscopy (UV–vis), Field emission gun scanning electron microscopy (FEG-SEM), X-ray energy dispersive spectroscopy (EDX), Transmission electron microscopy (TEM), Selected-area electron diffraction (SAED) and Fourier transform infra-red spectroscopy (FTIR). The results indicated that AgNPs formed were spherical in shape with size ranging from 14 to 40 nm with an average diameter 28.47 nm. Furthermore, it was observed that the AgNPs exhibited an antibacterial activity against different Gram positive and Gram negative microorganisms. Our report confirmed that the ALE is a very good eco-friendly and nontoxic bioreductant for the synthesis of AgNPs and opens up further opportunities for fabrication of antibacterial drugs, medical devices and wound dressings.
KeywordsAnnona squamosa L. Antibacterial activity Green synthesis Nanomedicine Silver nanoparticles
Annona squamosa L. Leaf Extract
X-ray Energy Dispersive Spectroscopy
Fourier Transform Infrared Spectroscopy
Selected Area Electron Diffraction
Field Emission Gun Scanning Electron Microscopy
Transmission Electron Microscopy
UBJ thanks Council of Scientific and Industrial Research (CSIR), New Delhi, India for providing SRF and VAB thanks Indian National Science Academy, New Delhi, India, for Senior Scientist Fellowship. We acknowledge the staffs SAIF, IIT-Mumbai, for FEG-SEM and TEM analysis.
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