Thermometry and interpretation of body temperature
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This article reviews the historical development and up-to-date state of thermometric technologies for measuring human body temperature (BT) from two aspects: measurement methodology and significance interpretation. Since the first systematic and comprehensive study on BT and its relation to human diseases was conducted by Wunderlich in the late 19th century, BT has served as one of the most fundamental vital signs for clinical diagnosis and daily healthcare. The physiological implication of BT set point and thermoregulatory mechanisms are briefly outlined. Influential determinants of BT measurement are investigated thoroughly. Three types of BT measurement, i.e., core body temperature, surface body temperature and basal body temperature, are categorized according to its measurement position and activity level. With the comparison of temperature measurement in industrial fields, specialties in technological and biological aspects in BT measurement are mentioned. Methodologies used in BT measurement are grouped into instrumental methods and mathematical methods. Instrumental methods utilize results of BT measurements directly from temperature-sensitive transducers and electronic instrumentations by the combination of actual and predictive measurement, invasive and noninvasive measurement. Mathematical methods use several numerical models, such as multiple regression model, autoregressive model, thermoregulatory mechanism-based model and the Kalman filter-based method to estimate BT indirectly from some relevant vital signs and environmental factors. Thermometry modalities are summarized on the dichotomies into invasive and noninvasive, contact and noncontact, direct and indirect, free and restrained, 1-D and n-D. Comprehensive interpretation of BT has an equal importance as the measurement of BT. Two modes to apply BT are classified into real-time applications and long-term applications. With rapid advancement in IoT infrastructure, big data analytics and AI platforms, prospects for future development in thermometry and interpretation of BT are discussed.
KeywordsBody temperature Thermometry Thermometer Body temperature measurement Body temperature interpretation Body temperature analysis
This study was supported in part by the Competitive Research Fund 2018-P-14 of the University of Aizu.
Compliance with ethical standards
Conflict of interest
The author declares that he has no conflict of interest.
This article does not contain any studies with human participants or animals performed by the author.
- 2.Wunderlich CA. On the temperature in diseases: a manual of medical thermometry. Oxford: The New Sydenham Society; 1871.Google Scholar
- 4.Cabej NR. Epigenetic principles of evolution—1. control systems and determination of phenotypic traits in Metazoans. In Cabej NR, editor. Amsterdam: Elsevier; 2012; 3:38.Google Scholar
- 5.Kelly GS. Body temperature variability (Part 1): a review of the History of body temperatureand its variability due to site selection, biological rhythms, fitness, and aging. Altern Med Rev. 2006;11(4):278–93.Google Scholar
- 8.Traditional Chinese medicine undisclosed recipe network. On the application of “cold head and warm feet. 21 July 2017. http://www.21nx.com/21nx/html/zhuanti/zhongyiyangsheng/2017/0721/62178.html. Accessed 28 Nov 2018.
- 9.Gao D. A collection of Chinese ancient medical works unearthed in 20th Century—commentary on Mountain Zhang Jia’s inscribed bamboo slips “Pulseology”, Chengdu, China. Chengdu: Chengdu Publishing Company; 1992.Google Scholar
- 10.Wikipedia. Ole Rømer. Accessed 23 Nov 2018. https://en.wikipedia.org/wiki/Ole_R%C3%B8mer. Accessed 1 Dec 2018.
- 11.Timetoast timelines. History of the Thermometer. https://media.timetoast.com/timelines/history-of-the-thermometer–9.Accessed 1 Dec 2018.
- 15.Tagawa T, Tamura T, Oberg AP. Biomedical sensors and instruments. Boca Raton: CRC Press; 2011.Google Scholar
- 17.Ruhle AR. Solid-state temperature sensor outperforms previous transducers. Electronics. 1975;48(6):127–30.Google Scholar
- 19.Rogalski, A. Next decade in infrared detectors in Proc. SPIE 10433. Electro-optical and Infrared systems: technology and applications. Warsaw, Poland; 2017.Google Scholar
- 20.Terumo Corporation. Terumo moves from Mercury to electronic thermometers. http://www.terumo.com/about/terumostory/1921_2001/cat5_2.html.
- 23.Lim CL, Byrne C, Lee JK. Human thermoregulation and measurement of body temperature in exercise and clinical settings. Ann Acad Med Singapore. 2008;37:347–53.Google Scholar
- 25.Grassl T, Ventur M, Koch J, Sattler F. Double temperature sensor. USA atent US 8,708,926 B2. 29 Apr 2014.Google Scholar
- 31.Huang M, Tamura T, Tang Z, Chen W, Kanaya S. Structural optimization of a wearable deep body thermometer: from theoretical simulation to experimental verification. J Sens. 2016;2016:1–7.Google Scholar
- 36.Gribok AV, Rumpler W, Buller M, Hoyt R. Predicting core temperature in humans using autoregressive model with exogenous inputs. The FASEB Journal. 2011;25:1052–3.Google Scholar
- 40.Sim S, Yoon H, Ryou H, Park K. Estimation of body temperature rhythm based on heart activity parameters in daily life. in 36th annual International conference of the IEEE Engineering in Medicine and Biology Society, 2014. Chicago, Illinois, USA.Google Scholar
- 41.Tamura T, Huang M, Togawa T. Body Temperature, Heat Flow, and Evaporation. in Seamless Health care Monitoring. Springer International Publishing AG. 2018; 281-307.Google Scholar
- 42.de Souza MA, Paz AAC, Sanches IJ, Nohama P, Gamba HR. 3D Thermal medical image visualization tool: Integration between MRI and thermographic images in 36th annual International conference of the IEEE Engineering in Medicine and Biology Society, 2014. Chicago, IL, USA.Google Scholar
- 45.Wikipedia. Human body temperature. https://en.wikipedia.org/wiki/Human_body_temperature#cite_note-pmid18788094-2. Accessed 5 Dec 2018.
- 46.Longo DL, Fauci A, Kasper D, Hauser S, Jameson J, Loscalzo J. Harrison’s principles of internal medicine, (18 ed.). New York: McGraw-Hill; 2011. p. 4012.Google Scholar
- 47.Asayama M. Guideline for the prevention of heat disorder in Japan. Global Environ Res. 2009;13(1):19–25.Google Scholar
- 49.Çam R, Yönem H, Özsoy H. Core body temperature changes during surgery and nursing management. Clin Med Res. 2016;5(2–1):1–5.Google Scholar
- 51.Habash R, Bansal R, Krewski D, Alhafid H. Thermal therapy, part 2: hyperthermia techniques. Crit Rev Biomed Eng. 2006;34(6):451–542.Google Scholar
- 52.Healthline media. Benefits of Cryotherapy.https://www.healthline.com/health/cryotherapy-benefits. Accessed 1 Dec 2018.
- 54.Huang M, Chen W, Nemoto T. Core temperature rhythm of bedridden patients with sequelae of cerebral infarction in the 49th annual conference of Japanese society of medical and biomedical engineering. Osaka, Japan. 2010.Google Scholar
- 55.Huang M, Tamura T, Chen W, Kitamura K, Nemo T, Kanaya S. Characterization of ultradian and circadian rhythms of core body temperature based on wavelet analysis in Conf Proc IEEE Eng Med Biol Soc. 2014. Chicago, Illinois, USA.Google Scholar
- 56.Chen W, Kitazawa M, Togawa T. HMM-based estimation of menstrual cycle from skin temperature during sleep in 30th annual International IEEE EMBS conference. Vancouver, British Columbia, Canada. 20–24 Aug 2008.Google Scholar
- 58.Ran’s Night. QOL Corporation. http://rans-night.jp/. Accessed 13 Nov 2018.
- 61.Nippon Avionics Co., Ltd. Thermo Mirror SX-01 series. http://www.avio.co.jp/jp/news/2011/0111-thermo-mirror.html.Accessed 11 Dec 2018.
- 63.Halberg F, Cornélissen G. Rhythms and blood pressure. Ann 1st Super Sanita. 1993;29(4):647–65.Google Scholar
- 64.Halberg F, Cornélissen G, Wang Z, Wan C, Ulmer W, Katinas G, Singh R, Singh R, Singh RK, Gupta B, Singh R, Kumar A, Kanabrocki E, Sothern RB, Rao G, Bhatt ML, Srivastava M, Rai G, Singh S, Pati AK, Nath P, Halberg F, Halberg J, Schwartzkopff O, Bakken E, Shastri SVK. Chronomics: circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond. J Exp Ther Oncol. 2003;3(5):223–60.CrossRefGoogle Scholar