Biomedical Engineering Letters

, Volume 5, Issue 2, pp 73–78 | Cite as

Enhancement of bone quality and longitudinal growth due to free-fall motion in growing rats

  • Seungkwan Cho
  • Sinae Eom
  • Dong-Hyun Seo
  • Jihyeong Park
  • Chang-Yong Ko
  • Han Sung Kim
Original Article

Abstract

Objectives

This study is to investigate the synchronous phenomena between bone quality and longitudinal length in a same subject affected by landing exercise. Physical exercise on the ground induces external loading to human body due to resistance from ground which can activate bone generation or remodeling. Especially, when the impact stimulation is applied to bone, it may improve bone quality and lengthening.

Methods

6-week-old male Wistar rats were randomly allocated to one of two conditions: free fall from 40 cm-height (I40; n = 7), and control (IC; n = 7). The impact stimulations were administered to the free fall groups, 10 times/day, and 5 days/week for 8 weeks. Structural parameters and longitudinal length of tibia were measured to quantitatively evaluate the variation in morphological characteristics and bone length with maturing.

Results

The landing impact seems to be commonly effective on the enhancement of bone quality as well as longitudinal growth. However, the extent of enhancement may be more dominant in bone quality than longitudinal growth. On the other hand, the ratio of longitudinal growth seems to be dependent on the duration of stimuli whereas the enhancement of bone quality does not.

Conclusions

This study verified that free-falls exercise can be effective on the enhancement of bone qualities and promotion of vertical growth in long bones. We expect that it might be possible for the moderate impact stimulation to be proposed as an aid for prevention of bone loss and promotion of bone lengthening.

Keywords

Bone quality Longitudinal length Free-fall motion Bone adaptation Growing rat Micro-computer tomography (micro-CT) 

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References

  1. [1]
    Umemura Y, Ishiko T, Tsujimoto H, Miura H, Mokushi N, Suzuki H. Effects of jump training on bone hypertrophy in young and old rats. Int J Sports Med. 1995; 16(6):364–7.CrossRefGoogle Scholar
  2. [2]
    Bassey EJ, Ramsdale SJ. Increase in femoral bone density in young women following high-impact exercise. Osteoporos Int. 1994; 4(2):72–5.CrossRefGoogle Scholar
  3. [3]
    Umemura Y, Ishiko T, Yamauchi T, Kurono M, Mashiko S. Five jumps per day increase bone mass and breaking force in rats. J Bone Mineral Res. 1997; 12(9):1480–5.CrossRefGoogle Scholar
  4. [4]
    Chilibeck PD, Sale DG, Webber CE. Exercise and bone mineral density. Sports Med. 1995; 19(2):103–22.CrossRefGoogle Scholar
  5. [5]
    Welch JM, Weaver CM, Turner CH. Adaptations to free-fall impact are different in the shafts and bone ends of rat forelimbs. J Appl Physiol. 2004; 97(5):1859–65.CrossRefGoogle Scholar
  6. [6]
    Turner CH. Three rules for bone adaptation to mechanical stimuli. Bone. 1998; 23(5):399–407.CrossRefGoogle Scholar
  7. [7]
    Adrian MJ, Laughlin CK. Magnitude of ground reaction forces while performing volleyball skills. In: Matsui H, Kobayashi K, editors. Biomechanics VIII-B. Champaign, IL Human Kinetics; 1983. pp. 903–14.Google Scholar
  8. [8]
    Kato T, Serashima T, Yamashita T, Hatanaka Y, Honda A, Umemura Y. Effect of low-repetition jump training on bone mineral density in young women. J Appl Physiol. 2006; 100(3):839–43.CrossRefMATHGoogle Scholar
  9. [9]
    Richards DP, Ajemian SV, Willey JP, Zernicke RF. Knee joint dynamics predict patellar tendinitis in elite volleyball players. Am J Sports Med. 1996; 24(5):676–83.CrossRefGoogle Scholar
  10. [10]
    Ju YI, Sone T, Ohnaru K, Tanaka K, Yamaguchi H, Fukunaga M. Effects of different types of jump impact on trabecular bone mass and microarchitecture in growing rats. PLoS One. 2014; doi: 10.1371/journal.pone.0107953.Google Scholar
  11. [11]
    Lin HS, Huang TH, Wang HS, Mao SW, Tai YS, Chju HT, Cheng KY, Yang RS. Short-term free-fall landing causes reduced bone size and bending energy in femora of growing rats. J Sports Sci Med. 2013; 12(1):1–9.Google Scholar
  12. [12]
    Welch JM, Turner CH, Devareddy L, Arjmandi BH, Weaver CM. High impact exercise is more beneficial than dietary calcium for building bone strength in the growing rat skeleton. Bone. 2008; 42(4):660–8.CrossRefGoogle Scholar
  13. [13]
    Honda A, Umemura Y, Nagasawa S. Effect of high-impact and low-repetition training on bones in ovariectomized rats. J Bone Miner Res. 2001; 16(9):1688–93.CrossRefGoogle Scholar
  14. [14]
    Forwood MR, Owan I, Takano Y, Turner CH. Increased bone formation in rat tibiae after a single short period of dynamic loading in vivo. Am J Physiol. 1996; 270(3 Pt 1):E419–23.Google Scholar
  15. [15]
    Judex S, Zernicke RF. High-impact exercise and growing bone: relation between high strain rates and enhanced bone formation. J Appl Physiol. 2000; 88(6):2183–91.Google Scholar
  16. [16]
    Notomi T, Okazaki Y, Okimoto N, Saitoh S, Nakamura T, Suzuki M. A comparison of resistance and aerobic training for mass, strength and turnover of bone in growing rats. Eur J Appl Physiol. 2000; 83(6):469–74.CrossRefGoogle Scholar
  17. [17]
    Notomi T, Lee SJ, Okimoto N, Okazaki Y, Takamoto T, Nakamura T, Suzuki M. Effects of resistance exercise training on mass, strength, and turnover of bone in growing rats. Eur J Appl Physiol. 2000; 82(4):268–74.CrossRefGoogle Scholar
  18. [18]
    Fuchs RK, Bauer JJ, Snow CM. Jumping improves hip and lumbar spine bone mass in prepubescent children: a randomized controlled trial. J Bone Mineral Res. 2001; 16(1):148–56.CrossRefGoogle Scholar
  19. [19]
    Khan K, McKay H, Kannus P, Bailey D, Wark J, Bennell K. Physical activity and bone health. Champaign, IL Human Kinetics; 2001. Physical activity and bone health. 2001. Human Kinetics.MATHGoogle Scholar
  20. [20]
    Frost HM. Bone’s mechanostat: a 2003 update. Anat Rec Part A 2003; 275(2):1081–101.MathSciNetCrossRefGoogle Scholar
  21. [21]
    Arriola F, Forriol F, Cañadell J. Histomorphometric study of growth plate subjected to different mechanical conditions (compression, tension and neutralization): an experimental study in lambs mechanical growth plate behavior. J Pediatr Orthop B. 2001; 10(4):334–8.Google Scholar
  22. [22]
    Ju YI, Sone T, Okamoto T, Fukunaga M. Jump exercise during remobilization restores integrity of the trabecular architecture after tail suspension in young rats. J Appl Physiol. 2008; 104(6):1594–600.CrossRefMATHGoogle Scholar
  23. [23]
    Carter DR, Fyhrie DP, Whalen RT. Trabecular bone density and loading history: regulation of connective tissue biology by mechanical energy. J Biomech. 1987; 20(8):785–94.CrossRefGoogle Scholar

Copyright information

© Korean Society of Medical and Biological Engineering and Springer 2015

Authors and Affiliations

  • Seungkwan Cho
    • 1
    • 2
  • Sinae Eom
    • 1
  • Dong-Hyun Seo
    • 1
    • 2
  • Jihyeong Park
    • 1
    • 2
  • Chang-Yong Ko
    • 3
  • Han Sung Kim
    • 1
    • 2
  1. 1.Department of Biomedical Engineering, College of Health ScienceYonsei UniversityWonju, GangwonKorea
  2. 2.Yonsei-Fraunhofer Medical Device Lab.Wonju, GangwonKorea
  3. 3.Korea Orthopedics & Rehabilitation Engineering CenterIncheonKorea

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