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Oral semaglutide significantly reduces low-density lipoprotein cholesterol level

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Data availability

The data that support the findings of this study are not publicly available due to the confidentiality of the participants; for example, they contain information that could compromise the privacy of research participants, but are available from the corresponding author upon reasonable request.

Abbreviations

AST:

Aspartate aminotransferase

ALT:

Aspartate aminotransferase

γ-GTP:

γ-Glutamyl transpeptidase

eGFR:

Estimated glomerular filtration rate

UACR:

Urinary albumin/creatinine ratio

References

  1. Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pederson SD, Tack CJ, Thomsen M, Vilsbøll T, Warren ML, Bain SC, PIONEER 6 Investigators. Oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2019;381:841–51.

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  2. Dahl K, Brooks A, Almazedi F, Hoff ST, Boschini C, Baekdal TA. Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes Obes Metab. 2021;23(7):1594–603.

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Funding

No funding received.

Author information

Authors and Affiliations

Authors

Contributions

Shuichi Okada and Kihachi Ohshim acared for the patient. Shuichi Okada, Kazuya Okada, Koji Kikkawa, Junichi Okada, Eijiro Yamada, Tsugumichi Saito, Tetsuro Andou, and Kihachi Ohshima attended the clinical conferences on this patient and made important suggestions for the differential diagnosis and therapeutic strategy. Shuichi Okada, and Junichi Okada prepared the manuscript.

Corresponding author

Correspondence to Shuichi Okada.

Ethics declarations

Statement of ethics

The study protocol was reviewed and approved by the review board of Hidaka Hospital (approved reference: 336) on 17 July 2021. The research complies with the guidelines for human studies in accordance with the World Medical Association Declaration of Helsinki. Written informed consent was obtained from the patient for publication of this manuscript and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Conflict of interest

None of the authors have any potential conflicts of interest associated with this case presentation.

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Cite this article

Okada, S., Okada, K., Okada, J. et al. Oral semaglutide significantly reduces low-density lipoprotein cholesterol level. Int J Diabetes Dev Ctries (2023). https://doi.org/10.1007/s13410-023-01259-4

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  • DOI: https://doi.org/10.1007/s13410-023-01259-4

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