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Diabetes in southern Iran: a 16-year follow-up of mortality and years of life lost

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International Journal of Diabetes in Developing Countries Aims and scope Submit manuscript

Abstract

Background

Diabetes mellitus (DM) had one of the highest global disease burdens and is associated with premature morbidity, mortality, and reduced life expectancy. There has been little study regarding mortality and years of life lost attributable to DM in low-and-middle income countries.

Methods

In this cross-sectional study, mortality rate and years of life lost (YLL) due to diabetes and its complications were examined during the years 2004–2019. Death statistics were collected through electronic registration of death of ministry of health and medical education for Fars province. Age standardized mortality rate (ASR) and joinpoint regression analysis carried out.

Results

A total of 6,403 deaths due to diabetes and its complications were recorded. Of these, 53.11% (3,401 cases) were women. The total YLL during the same period was 35,664 (1.13 per 1000 people) in men, and 42,459 (1.37 per 1000 people) in women. Diabetes resulted in a total of 78,123 YLL with an average 12 years of life lost per person with diabetes. According to the joinpoint regression, the 16-year trend in the YLL due to diabetes and its complications was increasing. The APC (annual percent change) was 4.7% (95% CI 1.9–7.5, p=0.002) for men, and 4.5% (95% CI 2.9–6.1, p<0.001) for women.

Conclusions

In this study, we found that from 2004 to 2019, the crude mortality rate, age standardized rate, and years of life lost due to diabetes were on the rise. We found obvious sex differences in diabetes-related deaths. The highest YLLs were in the age range 50–64. An accurate estimation of diabetes mortality could provide empirical support for future diabetes prevention and control strategies, determine priorities in health protection, and provide a basis for accurate prevention and control of diabetes in different regions and groups.

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Data availability

The data for the current study will not be shared publicly.

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Authors and Affiliations

  1. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

    Habibollah Azarbakhsh

  2. Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Mohammad Hossein Sharifi

  3. Research Center for Health Sciences, Institute of Health, Department of Epidemiology, Shiraz University of Medical Sciences, Shiraz, Iran

    Jafar Hassanzadeh

  4. Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK

    Rebecca Susan Dewey

  5. Shiraz University of Medical Sciences, Shiraz, Iran

    Maryam Janfada

  6. Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Alireza Mirahmadizadeh

Authors
  1. Habibollah Azarbakhsh
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  2. Mohammad Hossein Sharifi
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  3. Jafar Hassanzadeh
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  4. Rebecca Susan Dewey
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  6. Alireza Mirahmadizadeh
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Contributions

AH was responsible for the field working including data collection and management and wrote the discussion. JM collected data and wrote the manuscript. HJ wrote the manuscript. MA collected data and edited the final version of the manuscript. SMH has done the analysis of data and DRS wrote the manuscript and edited English language. All authors approved the final version of the manuscript and agreed to be accountable for all aspects of the work.

Corresponding author

Correspondence to Alireza Mirahmadizadeh.

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Ethics approval

The protocol describing this study was reviewed and approved by the ethics committee of Shiraz University of Medical Sciences (reference: IR.SUMS.REC.1399.772). All aspects of the study were conducted according to the University Code of Ethics.

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The authors declare no competing interests.

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Azarbakhsh, H., Sharifi, M.H., Hassanzadeh, J. et al. Diabetes in southern Iran: a 16-year follow-up of mortality and years of life lost. Int J Diabetes Dev Ctries 43, 574–580 (2023). https://doi.org/10.1007/s13410-022-01125-9

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  • DOI: https://doi.org/10.1007/s13410-022-01125-9

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