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Shear wave elastography in evaluation of carotid elasticity in the type 2 diabetes mellitus patients with nonalcoholic fatty liver disease

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Abstract

Purpose

Using shear wave elastography (SWE) to assess carotid elasticity in the type 2 diabetes mellitus (T2DM) patients with non-alcoholic fatty liver disease (NAFLD).

Methods

There were 98 patients diagnosed T2DM in our hospital, including 35 cases without NAFLD (group A), 33 cases with mild NAFLD (group B), and 30 cases with moderate to severe NAFLD (group C) according to the classification standard of fatty liver. There was no plaque by carotid ultrasound in all the selected patients. The left carotid intima-media thickness (IMT), standard carotid arterial systolic diameter (Ds), standard carotid arterial diastolic diameter (Dd), and systolic peak velocity (PSV) were measured by routine two-dimensional and M-mode ultrasound, and the stiffness coefficient (β) is obtained by calculation. Shear wave elastography (SWE) was used to measure the anterior wall of the left carotid artery values of longitudinal elastic modulus, including the mean values of mean elastic modulus (MEmean), the maximum elastic modulus (MEmax), and minimum elastic modulus (MEmin) at the end of diastole.

Results

There was no significant difference in Ds, Dd, and PSV among the groups (all p > 0.05). In group C, IMT, β, MEmean, MEmax, and MEmin increased significantly compared with groups A and B (all p < 0.05). Compared with group A, MEmean, MEmax, and MEmin increased in group B (all p < 0.05), while IMT and β were no significant difference (both p > 0.05).

Conclusion

SWE can quantitatively evaluate the carotid elasticity of the T2DM patients with NAFLD.

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Acknowledgment

We thank Prof. Li for guidance in study design and manuscript revision. In addition, we gratefully acknowledge the support and help from the Department of Ultrasound of the Second Affiliated Hospital of Dalian Medical University.

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  1. Mengmeng Zhang and Lian Tang contributed equally to this work.

Authors and Affiliations

  1. Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, China

    Mengmeng Zhang, Lian Tang, Xiuxiu Cui, Tingting Yu, Zhen Li, Xiya Li & Guangsen Li

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  1. Mengmeng Zhang
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  2. Lian Tang
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  3. Xiuxiu Cui
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  7. Guangsen Li
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Correspondence to Guangsen Li.

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Zhang, M., Tang, L., Cui, X. et al. Shear wave elastography in evaluation of carotid elasticity in the type 2 diabetes mellitus patients with nonalcoholic fatty liver disease. Int J Diabetes Dev Ctries 43, 191–198 (2023). https://doi.org/10.1007/s13410-022-01097-w

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  • DOI: https://doi.org/10.1007/s13410-022-01097-w

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