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Helicobacter pylori infection in elderly Chinese patients with type 2 diabetes

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Abstract

The relationship between Helicobacter pylori infection and diabetes is unclear, especially in elderly people. The aims of this study were to determine the possible relationship between H. pylori infection and type 2 diabetes (T2DM) in elderly subjects. In total, 238 T2DM patients (83.66 ± 3.10 years) and 704 non-diabetic patients (83.29 ± 3.17 years) were included. We measured the glycated hemoglobin level, lipid profile, presence of H. pylori using the urea breath test, and fasting serum insulin level. The H. pylori infection rate was 45.0 and 39.6 % in T2DM patients and control, respectively. The results were statistically insignificant. In the logistic regression analysis of 238 T2DM patients (including age, sex, diabetes, body mass index, the duration of diabetes, and the levels of serum total cholesterol, triglyceride, hemoglobin A1C, and insulin), no factors selected were associated with H. pylori infection. The H. pylori infection rate may not be increased in elderly Chinese T2DM patients. However, further studies are needed to confirm our conclusion.

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Author notes

    Authors and Affiliations

    1. Zhejiang Provincial People’s Hospital, Hangzhou, Zhejiang, China

      Haijian He

    2. Department of Nephrology, Zhejiang Provincial People’s Hospital, Hangzhou, Zhejiang, China

      Yueming Liu

    Authors
    1. Haijian He
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    2. Yueming Liu
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    Correspondence to Haijian He.

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    The authors declare that they have no competing interests.

    Ethics approval and consent to participate

    This study was approved by our hospital’s regional ethics committee, and all patients signed informed consent.

    Additional information

    Haijian He and Yueming Liu contributed equally to this work.

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    Cite this article

    He, H., Liu, Y. Helicobacter pylori infection in elderly Chinese patients with type 2 diabetes. Int J Diabetes Dev Ctries 36, 132–135 (2016). https://doi.org/10.1007/s13410-015-0449-2

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    • DOI: https://doi.org/10.1007/s13410-015-0449-2

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