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A web-based interactive lifestyle modification program improves lipid profile and serum adiponectin concentrations in patients with metabolic syndrome: the “Red Ruby” study

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Abstract

The effectiveness of internet-based programs in prevention and treatment of metabolic syndrome has not been fully explored. In the present study, we investigate the effect of a 6-month web-based interactive lifestyle modification program on anthropometric variables and biochemical risk factors of cardiovascular disease. The study had been carried out among 160 patients with metabolic syndrome (intervention, n = 80; control, n = 80). The primary outcomes were change in anthropometric variables, fasting serum glucose (FSG), lipid profile, insulin sensitivity, and serum adiponectin concentrations in intervention and control groups. Significant reductions in anthropometric variables and serum lipids were observed in both intervention and control groups; however, reduction in waist-to-hip ratio (WHR), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) was only significant in intervention group (P < 0.05). Reduction in anthropometric variables and serum triglyceride, systolic and diastolic blood pressure, and liver enzymes were significant in intervention and control groups (P < 0.05) but in women decrease in FSG, TC, and LDL-C were only significant in intervention group (P < 0.05). The present study showed that a web-based intervention was effective in weight loss and improving cardio-metabolic factors in patients with metabolic syndrome after a 6-month intervention.

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Acknowledgments

This work was supported by Cardiovascular Research Center–Tabriz University of Medical Sciences (5/92/1228) and by the research undersecretary of Tehran University of Medical Sciences (97/130/1736) and has been registered in IRCT (Identifier: IRCT201111198132N1).

Conflict of interest

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

    Mahdieh Abbasalizad Farhangi, Mir-Mousa Mirinazhad & Alireza Yaghoubi

  2. Nutrition Research Center, Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran

    Mahdieh Abbasalizad Farhangi

  3. Health Education and Health Promotion Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

    Leila Jahangiry & Davoud Shojaeezade

  4. Mental Health Research Group, Health Metrics Research Center, Iranian Institute of Health Sciences Research, ACECR, Tehran, Iran

    Ali Montazeri

Authors
  1. Mahdieh Abbasalizad Farhangi
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  2. Leila Jahangiry
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Correspondence to Leila Jahangiry.

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Farhangi, M.A., Jahangiry, L., Mirinazhad, MM. et al. A web-based interactive lifestyle modification program improves lipid profile and serum adiponectin concentrations in patients with metabolic syndrome: the “Red Ruby” study. Int J Diabetes Dev Ctries 37, 21–30 (2017). https://doi.org/10.1007/s13410-015-0395-z

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  • DOI: https://doi.org/10.1007/s13410-015-0395-z

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