Skip to main content
Log in

Green soap formulation: an insight into the optimization of preparations and antifungal action

  • Original Article
  • Published:
Biomass Conversion and Biorefinery Aims and scope Submit manuscript

Abstract

Ultrasound-assisted extract of Acalypha indica was used to prepare the green soap formulation. Previously, D-optimal mixture design was used to optimize the mixture of oil components including coconut oil (A, 34–56%), soybean oil (B, 19–31%), castor oil (C, 14–23%), sunflower oil (D, 4–6%), and olive oil (E, 5–9%). Linear regression models were proposed to predict the responses, i.e., hardness (Y1), iodine (Y2), and iodine number saponification (INS) (Y3), and validated with a high degree of statistical accuracy (Fcal > Ftab; df = 4, p < 0.0001; R2 > 0.9950). Optimization results revealed that the formulation containing 44.57% A, 23.62% B, 17.44% C, 5.37% D, and 9.0% E would yield 41 Y1, 62 Y2, and 159 Y3. The chemical properties of the optimized soap formulation were quite comparable concerning the standard soap specifications (IS13498). Further, this formulation was supplemented with Acalypha indica extract to prepare the green soap, and its antifungal activity was determined using the agar dilution method.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Vijay M (1940) The Drug and Cosmetics Act, 18th edn. Eastern Book Company, New Delhi, pp 5–6

    Google Scholar 

  2. Shahbandeh M (2019) Global value of the cosmetics market 2018-2025. https://www.statista.com/statistics/585522/global-value-cosmetics-market/. Accessed 26 July 2020

  3. Shahbandeh M (2020) Cosmetics Industry - Statistics & Facts, https://www.statista.com/topics/3137/cosmetics-industry/. Accessed 26 July 2020

  4. Khan AD, Alam MN (2019) Cosmetics and their associated adverse effects: a review. J Appl Pharm Sci Res 2(1):1–6

    Google Scholar 

  5. Johansen JD, Rastogi SC, Menne T (1996) Threshold responses in cinnamic-aldehyde-sensitive subjects: results and methodological aspects. Contact Dermatitis 34(3):165–171

    Article  Google Scholar 

  6. FDA News Release (2016) https://www.fda.gov/news-events/press-announcements/fda-issues-final-rule-safety-and-effectiveness-antibacterial-soaps. Accessed 26 July 2020

  7. Sharma B (2000) Industrial Chemistry (Including Chemical Engineering). GOEL Publishing House, Meerut

    Google Scholar 

  8. Ahmed I (1984) Palm Oil Research Institute of Malaysia (PORIM). Selangor, Malaysia, pp: 1–17

  9. Thirunavukkarasu A, Nithya R (2011) Response surface optimization of critical extraction parameters for anthocyanin from Solanummelongena. J Bioprocess Biotechniq 1:103

    Google Scholar 

  10. Archana A, Divya Bharathi V, Saaboji S, Thirunavukkarasu A, Nithya R (2015) Optimization and extraction of phenolic compounds from Capcicum annuum using response surface methodology. Int J Emerg Res Manag Technol 4(7):204–211

    Google Scholar 

  11. Thirunavukkarasu A, Nithya R (2019) Response surface optimization of Cu (II) biosorption onto Candida tropicalis immobilized strontium alginate beads by Box-Behnken experimental design. J Environ Biotechnol Res 8(2):14–21

    Google Scholar 

  12. Rajarathinam N, Arunachalam T, Raja S, Selvasembian R (2020) Fenalan Yellow G adsorption using surface-functionalized green nanoceria: an insight into mechanism and statistical modelling. Environ Res 181:108920

    Article  Google Scholar 

  13. Thirunavukkarasu A, Nithya R (2020) Adsorption of acid orange 7 using green synthesized CaO/CeO2 composite: an insight into kinetics, equilibrium, thermodynamics, mass transfer and statistical models. J Taiwan Inst Chem Eng 111:78–96

    Article  Google Scholar 

  14. Nikzade V, Tehrani MM, Saadatmand-Tarzjan M (2012) Optimization of low-cholesterol-low-fat mayonnaise formulation: effect of using soy milk and some stabilizer by a mixture design approach. Food Hydrocoll 28(2):344–352

    Article  Google Scholar 

  15. Shaviklo AR, Rafipour F (2014) Consumer-based development and optimization of fish strudel using D-optimal mixture design. J Food Process Preserv 38(3):845–855

    Article  Google Scholar 

  16. Ramachandran J (2008) Herbs of Siddha medicine/the first 3D book on herbs. MuruganPatthipagam, Chennai, p 156

    Google Scholar 

  17. Burkill HM (1985) The useful plants of West Tropical Africa. Royal Botanic Gardens, Kew, UK. 2: 246

  18. Devi N, Prabhakaran J, Wahab F (2012) Phyto chemical analysis and enzyme analysis of endophytic fungi from Centella asiatica. Asian Pac J Trop Biomed 2(3):S1280–S1284

  19. Chekuri S, Arun Jyoti B, Sompaga S, Panjala S, Anupalli RR (2018) Evaluation of anti microbial and anti fungal activity of Acalypha indica L., leaf extract. Int J Pharmacogn Phytochem Res 10(1):48–51

  20. Arunachalam T, Karpagasundaram M, Rajarathinam N (2017) Ultrasound assisted green synthesis of cerium oxide nanoparticles using Prosopis juliflora leaf extract and their structural, optical and antibacterial properties. Mater Sci-Pol 35(4):791–798

    Article  Google Scholar 

  21. Kundu MK, Deb AT, Gupta SP (1977) A simple rapid method for direct determination of total fatty matter in soaps. FetteSeifenAnstrichmittel 79:285–288

    Article  Google Scholar 

  22. Watkin BFK, Elphin J (2011) The chemistry of agricultural fungicides and insecticides. Dickens Press, London

    Google Scholar 

  23. Joyner NT, Rini SJ (1939) Some notes on the determination of moisture and volatile matter in fats and oils. Oil Soap 16:233–236

    Article  Google Scholar 

  24. Maron SH, Ulevitch IN, Elder ME (1952) Determination of soap, acid, and alkali in synthetic latices. Anal Chem 24:1068–1070

    Article  Google Scholar 

  25. Wijs JJA (1929) The Wijs method as the standard for iodine absorption. Analyst 1929(54):12–14

    Article  Google Scholar 

  26. Lawson HW (1985) Standards for fats and oils. AVI Publishing Company, Westport

    Book  Google Scholar 

  27. McDaniel RS (2000) Essentially soap: the elegant art of handmade soap making, scenting, coloring & shaping. Krause Publications, Wisconsin

    Google Scholar 

  28. Balouiri M, Sadiki M, Ibnsouda SK (2016) Methods for in vitro evaluating antimicrobial activity: a review. J Pharm Anal 6(2):71–79

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Arunachalam Thirunavukkarasu.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Thirunavukkarasu, A., Nithya, R., Sivashankar, R. et al. Green soap formulation: an insight into the optimization of preparations and antifungal action. Biomass Conv. Bioref. 13, 299–310 (2023). https://doi.org/10.1007/s13399-020-01094-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13399-020-01094-1

Keywords

Navigation