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Study and Optimization of the Synthesis of Apatitic Nanoparticles by the Dissolution/Precipitation Method

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Abstract

In this work, we have studied and optimized the technique of the synthesis of hydroxyapatite by a new method called "dissolution/reprecipitation", with the aim of finding the appropriate operating conditions for the synthesis of apatitic nanoparticles. The optimum value of the size of the apatitic nanoparticles being 65 nm. The theoretical results presented by this experimental design have been verified: the experimental results are similar to the results estimated by this model. Scanning electron microscopy images confirm the morphology of apatitic nanoparticles and verify the validity of our mathematical modeling. Analysis by infrared spectroscopy and X-ray diffraction of the products obtained by the method shows that the final phases are pure and stoichiometric. The method of dissolving-reprecipitating apatitic nanoparticles has several advantages over other methods, such as purity and nanoscale sizes of the final phase. The new dissolution / reprecipitation method is a synthesis technique which makes it possible to prepare very pure hydroxyapatite nanoparticles without the intervention of precursors (salts) which generally generate impurities in the final product. The new method can then be used in the synthesis of apatitic biocomposites using biopolymers.

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Abbreviations

HAp:

Hydroxyapatite

TCP:

Tricalcium phosphate

DCPD:

Dicalcium Phosphate Dihydrate

RMSE:

Root mean square error

Dp:

Grain size (nm)

M:

Weight

V:

Volume

T:

Temperature

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Acknowledgements

The authors would like to thank both Mohammed Premier University and the Department of Chemistry, d'Al-hoceima Abdelmalek Essaadi University, and An-Najah National University for using their chemistry laboratories. The authors reported no funding for this manuscript.

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No funding was received on this work. It is self-sponsored.

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Authors and Affiliations

  1. Laboratory of Applied Chemistry and Environment, Team: Mineral Chemistry of Solids, Department of Chemistry, Faculty of Sciences, Mohammed 1St University, P.O. Box 717, 60000, Oujda, Morocco

    N. Akartasse, K. Azzaoui, E. Mejdoubi, L. L. Elansari & B. Hammouti

  2. Department of Chemistry, College of Science, An-Najah National University, Nablus, Palestinian Territories

    G. Hanbali, S. Jodeh & W. Jodeh

  3. Laboratory of Applied Sciences, National School of Applied Sciences d’Al-Hoceima Abdelmalek Essaadi University, Tangier, Morocco

    A. Lamhamdi

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  1. N. Akartasse
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  2. K. Azzaoui
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  3. E. Mejdoubi
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  4. G. Hanbali
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  5. L. L. Elansari
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All authors contributed equally.

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Correspondence to K. Azzaoui or S. Jodeh.

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Akartasse, N., Azzaoui, K., Mejdoubi, E. et al. Study and Optimization of the Synthesis of Apatitic Nanoparticles by the Dissolution/Precipitation Method. Arab J Sci Eng 47, 7035–7051 (2022). https://doi.org/10.1007/s13369-021-06283-2

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