Korea-Australia Rheology Journal

, Volume 28, Issue 1, pp 1–22 | Cite as

A review of hemorheology: Measuring techniques and recent advances

  • Patrícia C. Sousa
  • Fernando T. Pinho
  • Manuel A. Alves
  • Mónica S. N. Oliveira
Review

Abstract

Significant progress has been made over the years on the topic of hemorheology, not only in terms of the development of more accurate and sophisticated techniques, but also in terms of understanding the phenomena associated with blood components, their interactions and impact upon blood properties. The rheological properties of blood are strongly dependent on the interactions and mechanical properties of red blood cells, and a variation of these properties can bring further insight into the human health state and can be an important parameter in clinical diagnosis. In this article, we provide both a reference for hemorheological research and a resource regarding the fundamental concepts in hemorheology. This review is aimed at those starting in the field of hemodynamics, where blood rheology plays a significant role, but also at those in search of the most up-to-date findings (both qualitative and quantitative) in hemorheological measurements and novel techniques used in this context, including technical advances under more extreme conditions such as in large amplitude oscillatory shear flow or under extensional flow, which impose large deformations comparable to those found in the microcirculatory system and in diseased vessels. Given the impressive rate of increase in the available knowledge on blood flow, this review is also intended to identify areas where current knowledge is still incomplete, and which have the potential for new, exciting and useful research. We also discuss the most important parameters that can lead to an alteration of blood rheology, and which as a consequence can have a significant impact on the normal physiological behavior of blood.

Keywords

hemorheology blood viscosity blood viscoelasticity RBC deformability RBC aggregation 

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© Korean Society of Rheology (KSR) and the Australian Society of Rheology (ASR) and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Patrícia C. Sousa
    • 1
  • Fernando T. Pinho
    • 2
  • Manuel A. Alves
    • 1
  • Mónica S. N. Oliveira
    • 3
  1. 1.Departamento de Engenharia Química, CEFTFaculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto FriasPortoPortugal
  2. 2.CEFT, Departamento de Engenharia MecânicaFaculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto FriasPortoPortugal
  3. 3.James Weir Fluids Laboratory, Department of Mechanical and Aerospace EngineeringUniversity of StrathclydeGlasgowUnited Kingdom

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