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Developmental changes and effect on intramuscular fat content of H-FABP and A-FABP mRNA expression in pigs

  • Animal Genetics • Short Communication
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Abstract

H-FABP and A-FABP genes are considered as candidates for intramuscular fat (IMF) accretion. The aim of the present study was to assess the expression of H-FABP and A-FABP genes in m. longissimus dorsi (LD) and liver tissues of Laiwu and Lulai Black pig populations of different body weight (BW). Eighty-four barrows at different BW (30, 40, 50, 60, 70, 80, 90 and 100 kg, n = 6 per group) of Laiwu Black pig (no 100 kg group) and Lulai Black pig (no 30 kg group) were used to study the development changes of A-FABP and H-FABP mRNA expression and their relationships to IMF content. The results showed that, in both breeds, the IMF content increased continuously with growing (P < 0.05). The expression of H-FABP and A-FABP genes also increased with growing in LD tissue (P < 0.05), and reached a peak at 50 and 70 kg BW in Laiwu and Lulai Black pig, respectively. However, this regularity was not observed in liver tissue in both breeds. A positive correlation was just found between the A-FABP mRNA expression level in LD tissue and IMF content and BW in both breeds (P < 0.05). In conclusion, the A-FABP gene is strongly related to the development and function of IMF accretion in pigs.

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Acknowledgements

This work was supported by the National Project for Breeding Transgenic Pigs of China (no. 2011ZX08006-002), the National High-Tech Research and Development Program of China (863 Program) (no. 2008AA101008), Shandong Province Agricultural Animal Breeding Project of China (no. 2009LZ012-03) and the Natural Science Foundation of Shandong Province of China (no. Y2008D32).

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Correspondence to Hui Wang or Yong-Qing Zeng.

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Chen, QM., Wang, H., Zeng, YQ. et al. Developmental changes and effect on intramuscular fat content of H-FABP and A-FABP mRNA expression in pigs. J Appl Genetics 54, 119–123 (2013). https://doi.org/10.1007/s13353-012-0122-0

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  • DOI: https://doi.org/10.1007/s13353-012-0122-0

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