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Electrospun collagen and its applications in regenerative medicine

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Abstract

In recent years, electrospinning has increased in popularity as a processing technique for obtaining nanometer-to-micron diameter polymer fibers collected to form a nonwoven scaffold. It possesses the ability to process collagen into nanofibrous scaffolds which have been used for a number of applications, such as artificial vascular grafts and for wound repair. This paper offers a review of some of the basic yet essential aspects of producing nanofibrous scaffolds of collagen by electrospinning. A primer to collagen structure, cross-linking techniques, and electrospinning principles is provided, along with some of the many applications of these unique materials.

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Authors and Affiliations

  1. Department of Macromolecular Science and Engineering, Case Western Reserve University, 2100 Adelbert Road, Cleveland, OH, 44106, USA

    Matthew J. Fullana & Gary E. Wnek

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  1. Matthew J. Fullana
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  2. Gary E. Wnek
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Correspondence to Gary E. Wnek.

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Fullana, M.J., Wnek, G.E. Electrospun collagen and its applications in regenerative medicine. Drug Deliv. and Transl. Res. 2, 313–322 (2012). https://doi.org/10.1007/s13346-012-0087-x

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