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VirusDisease

, Volume 29, Issue 2, pp 173–179 | Cite as

Cross-sectional sero-prevalence study of Peste des Petits Ruminants (PPR) in goats of Syangja and Kaski districts of Nepal

  • Narayan Acharya
  • Shankar Prasad Poudel
  • Krishna Prasad Acharya
Original Article

Abstract

A cross-sectional study was conducted to determine sero-prevalence of Peste des Petits Ruminants (PPR) among goat population of outbreak suspected areas; Kaski and Syangja districts of Nepal. A total of 460 goat serum samples were tested by using c-ELISA for the presence of antibodies against PPR. Out of the 460 samples tested, 380 samples were found positive, giving overall sero-positivity of 82.60%. Significantly higher sero-prevalence was found (*P < 0.05) in females (87.50%) compared to males (70.45%) and crossbreed goats were found highly susceptible than the pure breed goats (*P < 0.05). Likewise, higher sero-prevalence of PPR was observed in adults and cross breed goats compared to their counterparts and significantly higher sero-prevalence was observed in Syangja district compared to Kaski. Thus, adults, females and cross-breeds populations of goats are at higher risk of PPR whereas geographically, goat population of Syangja district were found significantly prone to PPR. Appropriate control measures, such as ring vaccination can be followed to prevent the potential outbreak situation.

Keywords

Goats Peste des Petits Ruminants (PPR) Sero-prevalence Nepal 

References

  1. 1.
    Abdalla AS, Majok AA, El Malik KH, Ali AS. Sero-prevalence of peste des petits ruminants virus (PPRV) in small ruminants in Blue Nile, Gadaref and North Kordofan States of Sudan. J Public Heal Epidemiol. 2012;4:59–64.Google Scholar
  2. 2.
    Abubakar M, Rasool MH, Manzoor S, Saqalein M, Rizwan M, et al. Evaluation of risk factors for peste des petits ruminants virus in sheep and goats at the wildlife-livestock interface in Punjab province, Pakistan. Biomed Res Int. 2016;2016:7826245.PubMedPubMedCentralGoogle Scholar
  3. 3.
    Abubakar M, Zahur AB, Afzal M, Ali Q, Gonzales J. Peste des Petits Ruminants (PPR) in Pakistan: analysis of a national level serological data. Small Rumin Res. 2017;155:57–65.CrossRefGoogle Scholar
  4. 4.
    Abubakar M, Mahapatra M, Muniraju M, Arshed MJ, Khan EH, Banyard AC, et al. Serological detection of antibodies to peste des petits ruminants virus in large ruminants. Transbound Emerg Dis. 2017;64:513–9.CrossRefPubMedGoogle Scholar
  5. 5.
    Al-Majali AM, Hussain NO, Amarin NM, Majok AA. Seroprevalence of, and risk factors for, peste des petits ruminants in sheep and goats in Northern Jordan. Prev Vet Med. 2008;85:1–8.CrossRefPubMedGoogle Scholar
  6. 6.
    Annual Technical Report [Internet]. Tripureshwor, Kathmandu, Central Veterinary Laboratory, Department of Livestock Services, Ministry of Livestock Development, Government of Nepal. 2015. http://www.cvl.gov.np/uploads/files/5324820354.pdf. Accessed 22 Dec 2017.
  7. 7.
    Baazizi R, Mahapatra M, Clarke BD, Ait-Oudhia K, Khelef D, Parida S. Peste des petits ruminants (PPR): a neglected tropical disease in Maghreb region of North Africa and its threat to Europe. PLoS ONE. 2017;12:e0175461.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Balamurugan V, Saravanan P, Sen A, Rajak KK, Venkatesan G, Krishnamoorthy P, et al. Prevalence of peste des petits ruminants among sheep and goats in India. J Vet Sci. 2012;13:279–85.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Balamurugan V, Krishnamoorthy P, Raju DSN, Rajak KK, Bhanuprakash V, Pandey AB, et al. Prevalence of Peste-des-petits-ruminant virus antibodies in cattle, buffaloes, sheep and goats in India. Virusdisease. 2014;25:85–90.CrossRefPubMedGoogle Scholar
  10. 10.
    Balamurugan V, Das S, Raju DSN, Chakravarty I, Nagalingam M, Hemadri D, et al. Prevalence of peste des petits ruminants in goats in North-East India. Virusdisease. 2014;25:488–92.CrossRefPubMedPubMedCentralGoogle Scholar
  11. 11.
    Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gen Virol. 2010;91:2885–97.CrossRefPubMedGoogle Scholar
  12. 12.
    Banyard AC, Wang Z, Parida S. Peste des petits ruminants virus, eastern Asia. Emerg Infect Dis. 2014;20:2176–8.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Bello AM, Lawal JR, Dauda J, Wakil Y, Lekko YM, Mshellia ES, et al. Research for peste des petits ruminants (PPR) virus antibodies in goats, sheep and gazelle from Bauchi and Gombe states, North Eastern Nigeria. Direct Res J Agric Food Sci. 2016;4:193–8.Google Scholar
  14. 14.
    Bhaskar SR, Deshmukh VV, Chopade NA, Rautmare SS. Seroprevalence of Peste Des Petits Ruminants in Maharashtra. Indian J Anim Res. 2009;43:285–7.Google Scholar
  15. 15.
    Daniel WW, editor. Biostatistics: a foundation for analysis in the health sciences. 7th ed. New York: Wiley; 1999.Google Scholar
  16. 16.
    Dhar P, Sreenivasa B, Barrett T, Corteyn M, Singh R, Bandyopadhyay S. Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol. 2002;88:153–9.CrossRefPubMedGoogle Scholar
  17. 17.
    DoAH. Annual Epidemiological Bulletin. Tripureshwor, Kathmandu: Veterinary Epidemiological Centre, Directorate of Animal Health; 2015.Google Scholar
  18. 18.
    El-Yuguda AD, Abubakar MB, Nabi AB, Andrew A, Baba SS. Outbreak of peste des petits ruminant in an unvaccinated Sahel goat farm in Maiduguri, Nigeria. Afr J Biomed Res. 2008;12:83–7.Google Scholar
  19. 19.
    Islam M, Hasan A, Yousuf A, Islam UK, Mahfuz M, Khan A. Seroprevalence of Peste des Petits Ruminant Virus specific antibody in goats in different regions of Bangladesh. J Adv Vet Anim Res. 2016;7710:127–33.CrossRefGoogle Scholar
  20. 20.
    Janus A, Tresamol PV, Saseendranath MR, Vijayakumar K, Pillai UN. Seroprevalence of PPR in goats in Kerala by cELISA. J Vet Anim Sci. 2009;40:15–6.Google Scholar
  21. 21.
    Jha VK, Singh DB, Thakuri KC, Gautam SP. National workshop. In: Gurung TB, Joshi BR, Singh UM, Paudel KP, Shrestha BS, Rijal KP et al (eds) Research & development strategies for goat enterprises in Nepal. 2013. https://www.researchgate.net/profile/Tek_Gurung/publication/257143203_Proceedings_of_the_National_Workshop_on_Research_and_Development_Strategies_for_Goat_Enterprises_in_Nepal/links/0deec524bc1267ea34000000/Proceedings-of-the-National-Workshop-on-Research. Accessed 9 Nov 2017
  22. 22.
    Khakural GP. Surveillance of goat diseases in the Western Hills of Nepal. Nepal J Sci Technol. 2003;5:37–40.Google Scholar
  23. 23.
    Khakural GP, Upreti CR. Proceedings of the 3rd national workshop on livestock and fisheries research in Nepal. 1999. p. 148–52. http://coin.fao.org/coin-static/cms/media/22/14376249192440/a_compendium_of_livestock_and_fisheries_research_highlights_in_nepal.pdf. Accessed 9 Nov 2017.
  24. 24.
    Khan HA, Siddique M, Sajjad-Ur-Rahman, Abubakar M, Ashraf M. The detection of antibody against peste des petits ruminants virus in Sheep, Goats, Cattle and Buffaloes. Trop Anim Health Prod. 2008;40:521–7.CrossRefPubMedGoogle Scholar
  25. 25.
    Kihu SM, Gachohi JM, Ndungu EK, Gitao GC, Bebora LC, John NM, et al. Sero-epidemiology of Peste des petits ruminants virus infection in Turkana County, Kenya. BMC Vet Res. 2015;11:87.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Mahajan S, Agrawal R, Kumar M, Mohan A, Pande N. Risk of seroconversion to peste des petits ruminants (PPR) and its association with species, sex, age and migration. Small Rumin Res. 2012;104:195–200.CrossRefGoogle Scholar
  27. 27.
    Mariner JC, Jones BA, Rich KM, Thevasagayam S, Anderson J, Jeggo M, et al. The opportunity to eradicate peste des petits ruminants. J Immunol. 2016;196:3499–506.CrossRefPubMedGoogle Scholar
  28. 28.
    Mehmood A, Ali Q, Gadahi JA, Malik SA, Shah SI. Detection of peste des petits ruminants (PPR) virus antibodies in sheep and goat populations of the north west frontier province (NWFP) of Pakistan by competitive elisa (cELISA). Vet World. 2009;2:333–6.Google Scholar
  29. 29.
    Naing L, Winn T, Rusli BN. Practical issues in calculating the sample size for prevalence studies. Arch Orofac Sci. 2006;1:9–14.Google Scholar
  30. 30.
    Nizamani AR, Nizamani ZA, Umrani AP, Dewani P, Vandiar MA, Gandahi JA, et al. Prevalence of peste des petits ruminants virus antibodies in small Ruminantsin Sindh, Pakistan. J Anim Plant Sci. 2015;25:1515–9.Google Scholar
  31. 31.
    Ozkul A, Akca Y, Alkan F, Barrett T, Karaoglu T, Dagalp SB, et al. Prevalence, distribution, and host range of Peste des petits ruminants virus, Turkey. Emerg Infect Dis. 2002;8:708–12.CrossRefPubMedGoogle Scholar
  32. 32.
    Parida S, Muniraju M, Mahapatra M, Muthuchelvan D, Buczkowski H, Banyard AC. Peste des petits ruminants. Vet Microbiol. 2015;181:90–106.CrossRefPubMedPubMedCentralGoogle Scholar
  33. 33.
    Salih H, Elfadil A, Saeed I, Ali Y. Seroprevalence and risk factors of Peste des Petits Ruminants in sheep and goats in Sudan. J Adv Vet Anim Res. 2014;1:42–9.CrossRefGoogle Scholar
  34. 34.
    Sarker S, Islam H. Prevalence and risk factor assessment of peste des petits ruminants in goats in Rajshahi, Bangladesh. Vet World. 2011;4:546–9.CrossRefGoogle Scholar
  35. 35.
    Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, et al. Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis. 2009;15:299–301.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Indian Virological Society 2018

Authors and Affiliations

  • Narayan Acharya
    • 1
  • Shankar Prasad Poudel
    • 2
  • Krishna Prasad Acharya
    • 3
  1. 1.Texas Tech UniversityLubbockUSA
  2. 2.Institute of Agriculture and Animal Science (IAAS)Rampur, ChitwanNepal
  3. 3.Regional Veterinary Laboratory (RVL)PokharaNepal

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