Detection of Leptospirosis Bacteria in Rodent Urine by Surface Plasmon Resonance Sensor Using Graphene


In this paper, a graphene-coated surface plasmon resonance sensor is designed for the examination of Rodent urine which is responsible for Leptospirosis bacteria. Rodent urine is considered as sensing medium. Graphene surface is activated by phosphate-buffered saline solution for better attachment of Leptospirosis bacteria on its surface. Oliguria and Polyuria are the Rodent urine with high and low concentrations of Leptospirosis bacteria, respectively. The transfer matrix method is used for the formulation of reflection intensity of p-polarized light. The reflectance curves for angular interrogation are plotted and the results are obtained in terms of sensitivity, detection accuracy, and quality factor. The significantly high sensitivity and detection accuracy for Oliguria distinguishes it from Polyuria having lower sensitivity.


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Surjeet Raikwar is thankful to Dr. Abdul Kalam Technical University, Lucknow (India) for providing Research Grant Homi Bhabha Teaching Assistant Fellowship.

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Correspondence to Y. K. Prajapati.

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Raikwar, S., Prajapati, Y.K., Srivastava, D.K. et al. Detection of Leptospirosis Bacteria in Rodent Urine by Surface Plasmon Resonance Sensor Using Graphene. Photonic Sens (2020).

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  • Surface plasmon resonance sensor
  • active metal layer
  • Leptospirosis bacteria