Photonic Sensors

, Volume 7, Issue 1, pp 11–19 | Cite as

Photonic crystal based biosensor for the detection of glucose concentration in urine

  • Savarimuthu RobinsonEmail author
  • Nagaraj Dhanlaksmi
Open Access


Photonic sensing technology is a new and accurate measurement technology for bio-sensing applications. In this paper, a two-dimensional photonic crystal ring resonator based sensor is proposed and designed to detect the glucose concentration in urine over the range of 0 gm/dl-15 gm/dl. The proposed sensor is consisted of two inverted “L” waveguides and a ring resonator. If the glucose concentration in urine is varied, the refractive index of the urine is varied, which in turn the output response of sensor will be varied. By having the aforementioned principle, the glucose concentration in urine, glucose concentration in blood, albumin, urea, and bilirubin concentration in urine are predicted. The size of the proposed sensor is about 11.4 µm×11.4 µm, and the sensor can predict the result very accurately without any delay, hence, this attempt could be implemented for medical applications.


Biosensor photonic crystal refractive index urine glucose urea 


  1. [1]
    L. C. Clark and C. Lyons, “Electrode systems for continuous monitoring in cardiovascular surgery,” Annals of the New York Academy of Sciences, 1962, 102(1): 29–45.ADSCrossRefGoogle Scholar
  2. [2]
    S. I. Ahmad, “Studies on some biophysical aspects of human renal excretory fluid,” Ph.D. dissertation, Department of Physics, Jawaharlal Nehru Technological University, Hyderabad, India, 2010.Google Scholar
  3. [3]
    P. Sharma, S. K. Roy, and P. Sharan, “Design and simulation of photonic crystal based biosensor for detection of different blood components,” in Proceeding of IEEE Region 10 Symposium, Kulala Lumpur, Malaysia, pp. 171–176, 2014.Google Scholar
  4. [4]
    P. Sharma, P. Deshmukh, and P. Sharan, “Design and analysis of blood components by using optical sensor,” International Journal on Current Research, 2013, 5(8): 2225–2228.Google Scholar
  5. [5]
    P. Sharma and P Sharan, “Photonic crystal based sensor for detection of high glucose concentration in urine,” in Proceeding of Annual IEEE India Conference, vol. 19, pp. 184–191, 2015.Google Scholar
  6. [6]
    World Health Organization, Fact Sheet N312, Available online:, 2014.Google Scholar
  7. [7]
    Agency for Healthcare Research and Quality, Available online:, 2012.Google Scholar
  8. [8]
    Blood Glucose Monitoring-Wikipedia, The Free Encyclopedia, Available online: ng, 2014.Google Scholar
  9. [9]
    Fluorescent Glucose Biosensor the Free Encyclopedia, Available online:, 2015.Google Scholar
  10. [10]
    Diabetes Care-Blood Glucose Test Strips, Available online: http://www.diabetes_cara/diabetes-teststrips. html, 2014.Google Scholar
  11. [11]
    E. Yablonovitch, “Inhibited spontaneous emission in solid-state physics and electronics,” Physical Review Letters, 1987, 58(20): 2059–2062.ADSCrossRefGoogle Scholar
  12. [12]
    M. R. Lee and P. M. Fauchet, “Two-dimensional silicon photonic crystal based biosensor platform for protein detection,” Optics Express, 2007, 15(8): 4530–4535.ADSCrossRefGoogle Scholar
  13. [13]
    J. D. Joannopoulos, R. D. Meade, and J. N. Winn, Photonic crystal: modeling of flow of light. Princeton: Princeton University Press, 1995.Google Scholar
  14. [14]
    S. Robinson and R. Nakkeeran, “Investigation on two dimensional photonic crystal resonant cavity based band pass filter,” Optik-International Journal for Light and Electrons Optics, 2012, 123(5): 451–457.CrossRefGoogle Scholar
  15. [15]
    L. Li and G. Q. Liu, “Photonic crystal ring resonator channel drop filter,” Optik-International Journal for Light and Electrons Optics, 2013, 124(17): 2966–2968.CrossRefGoogle Scholar
  16. [16]
    B. J. Luff, R. D. Harris, J. S. Wilkinson, R. Wilson, and D. J. Schiffrin, “Integrated-optical directional couplerbiosensor,” Optics Letters, 1996, 21(8): 618–620.ADSCrossRefGoogle Scholar
  17. [17]
    T. Saranya, S. Robinson, and K. V. Shanthi, “Design and simulation of two dimensional photonic crystal ring resonator based four port wavelength demultiplexer,” International Journal of Innovative, Science, Engineering and Technology, 2013, 1(2): 154–161.Google Scholar
  18. [18]
    M. R. Rakhshani and M. A. Mansouri-Birjandi, “Wavelength demultiplexer using heterostructure ring resonators in triangular photonic crystal,” Telkomnika Indonesian Journal of Electrical Engineering, 2013, 11(4): 1721–1724.CrossRefGoogle Scholar
  19. [19]
    M. R. Rakhshani and M. A. Mansouri-Birjandi, “Design and optimization of photonic crystal triplexer for optical networks,” International Journal of Computer Science Issues, 2012, 9(4): 24–28.Google Scholar
  20. [20]
    A. Labbani and B. Abdelmadjid, “Design of photonic crystal triplexer with core-shell rod defects,” Chinese Physics Letters, 2015, 32(5): 63–65.CrossRefGoogle Scholar
  21. [21]
    J. H. Chen, Y. T. Huang, Y. L. Yang, and M. F. Lu, “Design, fabrication and characterization of Si-based ARROW photonic crystal bend waveguides and power splitters,” Journal of Applied Optics, 2012, 51(24): 5876–5884.CrossRefGoogle Scholar
  22. [22]
    M. M. Khan, “Nano structure based power splitter design by using 2D photonic crystals,” Journal of Modern Science and Technology, 2013, 1(1): 176–187.Google Scholar
  23. [23]
    R. Bchir, A. Bardaoui, and H. Ezzaouia, “Design of silicon-based two-dimensional photonic integrated circuits: XOR gate,” Journal of IET Optoelectronics, 2013, 7(1): 25–29.CrossRefGoogle Scholar
  24. [24]
    K. Fasihi, “High-contrast all-optical controllable switching and routing in nonlinear photonic crystals,” Journal of Lightwave Technology, 2014, 32(18): 3126–3131.ADSCrossRefGoogle Scholar
  25. [25]
    K. Cui, Q. Zhao, X. Feng, Y. Huang, Y. Li, D. Wang, et al., “Thermo-optic switch based on transmission-dip shifting in a double-slot photonic crystal waveguide,” Applied Physics Letters, 2012, 100(20): 1–4.CrossRefGoogle Scholar
  26. [26]
    J. M. Brosi, C. Koos, L. C. Andreani, M. Waldow, J. Leuthold, and W. Freude, “High-speed low-voltage electro-optic modulator with a polymer-infiltrated silicon photonic crystal waveguide,” Optics Express, 2008, 16(6): 4177–4191.ADSCrossRefGoogle Scholar
  27. [27]
    Y. Gao, R. J. Shiue, X. Gan, L. Li, P. Cheng, I. Meric, et al., “High-speed electro-optic modulator integrated with graphene-boron nitride heterostructure and photonic crystal nanocavity,” Nano Letters, 2015, 15(3): 2001–2005ADSCrossRefGoogle Scholar
  28. [28]
    S. Robinson and R. Nakkeeran, “Photonic crystal ring resonator based add-drop filter for CWDM systems,” Optik-International Journal for Light and Electrons Optics, 2013, 124(3): 3430–3435.CrossRefGoogle Scholar
  29. [29]
    H. Alipour-Banaei, F. Mehdizadeh, and M. Hassangholizadeh-Kashtiban, “A new proposal for PCRR-based channel drop filter using elliptical rings,” Physica E: Low-Dimensional Systems and Nanostructures, 2014, 56(2): 211–215.ADSCrossRefGoogle Scholar
  30. [30]
    P. Sharma, “Photonic crystal based ring resonator sensor for detection of glucose concentration for biomedical application,” International Journal of Emerging Technology and Advanced Engineering, 2014, 4(3): 702–706.Google Scholar
  31. [31]
    S. Olyaee and A. M. Bahabady, “Designing a novel photonic crystal nano-ring resonator for biosensor application,” Optical and Quantum Electronics, 2014, 53(6): 1881–1888.Google Scholar
  32. [32]
    S. Robinson and R. Nakkeeran, “PC based optical salinity sensor for different temperatures,” Photonic Sensors, 2012, 2(2): 187–192.ADSCrossRefGoogle Scholar
  33. [33]
    F. L. Hsiao and C. Lee, “Computational study of photonic crystal nano-ring resonator for biomedical sensing,” IEEE Sensors Journal, 2010, 10(7): 1185–1191.CrossRefGoogle Scholar
  34. [34]
    R. M. Silva, M. S. Ferreira, J. L. Santos, and O. Frazao, “Nanostrain measurement using chirped Bragg grating Fabry-Perot interferometer,” Photonic Sensors, 2012, 2(1): 77–80.ADSCrossRefGoogle Scholar
  35. [35]
    T. T. Mai, F. L. Hsiao, C. Lee, W. F. Xiang, C. C. Chen, and W. K. Choi, “Optimization and comparison of photonic crystal resonators for silicon microcantilever sensors,” Sensors and Actuators A Physical, 2011, 165(1): 16–25.CrossRefGoogle Scholar
  36. [36]
    K. Vijayashanthi and S. Robinson, “Two-dimensional photonic crystal based sensor for pressure sensing,” Photonic Sensors, 2014, 4(3): 248–253.ADSCrossRefGoogle Scholar
  37. [37]
    P. Sharma and P. Sharan, “Design of photonic crystal based biosensor for detection of glucose concentration in urine,” IEEE Sensors Journal, 2015, 15(2): 1035–1042.CrossRefGoogle Scholar
  38. [38]
    P. Sharma and P. Sharan, “An analysis and design of photonic crystal based biochip for detection of glycosuria,” IEEE Sensor Journal, 2015, 15(10): 5569–5575.CrossRefGoogle Scholar
  39. [39]
    F. Abdalmalek, “Design of a novel left-handed photonic crystal sensor operating in aqueous environment,” IEEE Photonic Sensors, 2011, 23(3): 188–190.ADSCrossRefGoogle Scholar
  40. [40]
    F. D. Gudagunti, P. Sharma, S. Talabattula, and V. Nainitej, “Early stage detection of breast cancer using hybrid photonic crystal ring resonator,” in Proceeding of IEEE International Conference on Advanced Communication Control and Computing Technologies, Ramanathapuram, pp. 1–4, 2014.Google Scholar
  41. [41]
    P. Sharan, S. M. Bharadwaj, F. D. Gudagunti, and P. Deshmukh, “Design and modeling of photonic sensor for cancer cell detection,” International Conference on the Impact of E-Technology on US, 2014, 40(14): 20–25.Google Scholar
  42. [42]
    R. D. Meade, A. M. Rappe, K. D. Brommer, and J. D. Joannopoulos, “Existence of a photonic band gap in two dimensional,” Applied Physics Letters, 1992, 61(4): 495–497.ADSCrossRefGoogle Scholar
  43. [43]
    J. D. Joannopoulos, P. R. Villeneuve, and S. Fan, “Photonic crystals: putting a new twist on light,” Nature, 1997, 386(6621): 143–149.ADSCrossRefGoogle Scholar

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  1. 1.Department of Electronics and Communication EngineeringMount Zion College of Engineering and TechnologyPudukkottai, Tamil NaduIndia

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