Abstract
We describe clinical characteristics of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infected children during the XBB.1.16 variant-driven surge in April, 2023 in India. A significantly higher positivity rate in young infants than in older children (37.4% vs 13.3%; P<0.001), and a predominance of respiratory symptoms were noticed. Notably, non-purulent conjunctivitis was found in 36.8% of SARS-CoV-2 positive infants. All recovered with symptomatic treatment as outpatients.
References
Huge jump in COVID-19 cases! Over 11,000 infections reported in last 24 hours. Accessed on April 15, 2023. Available from https://www.businesstoday.in/coronavirus/story/huge-jump-in-covid-19-cases-over-11000-infections-reported-in-last-24-hours-377357-2023-04-14
XBB.1.16, new Arcturus variant behind India’s COVID-19 surge. Accessed on April 15, 2023. Available from https://health.economictimes.indiatimes.com/news/industry/xbb-1–16-new-arcturus-variant-behind-indias-covid-19-surge/99495285
The Indian SARS-CoV-2 Genomics Consortium (INSACOG). Accessed on July 22, 2023. Available from https://inda.rcb.ac.in/insacog/statreportlineagegraph
Sarkar M, Ghosh A, Konar MC, Roy O, Mahapatra MK, Nandi M. Clinical characteristics of children with SARS-CoV-2 infection during the third wave of the pandemic: single center experience. Indian Pediatr. 2022;59:531–4.
Muthusamy S, Sarojam B, Sugunan S, et al. Clinical Profile and short-term outcome of children with acute SARS-CoV-2 infection during the first and second waves of the pandemic. Indian J Pediatr. 2022:1–7.
Güemes-Villahoz N, Burgos-Blasco B, García-Feijoó J, Sáenz-Francés F, Arriola-Villalobos P, Martinez-de-la-Casa JM, et al. Conjunctivitis in COVID-19 patients: frequency and clinical presentation. Graefes Arch Clin Exp Ophthalmol. 2020 Nov;258:2501–7.
Belser JA, Rota PA, Tumpey TM. Ocular tropism of respiratory viruses. Microbiol Mol Biol Rev. 2013;77:144–56.
Funding
Funding: None
Author information
Authors and Affiliations
Contributions
Contributors: VMV conceptualize and conducted the study, analyzed, and prepared the initial draft of the manuscript. PK helped in drafting and data analysis, gave valuable inputs in the interpretation of the data, and helped in editing the manuscript. Both authors approved the final version of the manuscript.
Corresponding author
Ethics declarations
Ethics clearance: IEC, Mangla Hospital & Research Centre, Bijnor; No. MHRC/IEC/2023/03, dated April 3, 2023.
Competing interests: None stated.
Rights and permissions
About this article
Cite this article
Vashishtha, V.M., Kumar, P. Conjunctival Involvement in Infants as an Unusual Symptom of Omicron XBB.1.16 Driven Surge. Indian Pediatr 60, 861–862 (2023). https://doi.org/10.1007/s13312-023-3020-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13312-023-3020-0