Abstract
This study aims to describe the clinical characteristics and outcome of 92 infants (aged <12 months) with community-acquired coronavirus disease 2019 (COVID-19) between March, 2020 and June, 2021 at a single center in Athens. Infants with COVID-19 developed mild disease (89, 96.7%), and were infected mostly by their household contacts (74, 80.4%). Disease complications were rare, indicating that hospitalization is the result of low threshold for admission rather than disease severity.
Article PDF
Avoid common mistakes on your manuscript.
References
Götzinger F, Santiago-García B, Noguera-Julián A, et al. COVID-19 in children and adolescents in Europe: A multinational, multicentre cohort study. Lancet Child Adolesc Health. 2020;4:653–61.
Mark EG, Golden WC, Gilmore MM, et al. Community-onset severe acute respiratory syndrome coronavirus 2 infection in young infants: A systematic review. J Pediatr. 2021;228:94–100.e3.
Raba AA, Abobaker A, Elgenaidi IS, et al. Novel coronavirus infection (COVID-19) in children younger than one year: A systematic review of symptoms, management and outcomes. Acta Paediatr. 2020;109:1948–55.
Bellini T, Rotulo GA, Caruggi S, et al. Characteristics of COVID-19 patients up to 6 months of age admitted to a paediatric emergency department. Acta Pediatr. 2021;https://doi.org/10.1111/apa.16166.
Public Health England (PHE). Understanding cycle threshold (Ct) in SARS-CoV-2 RT-PCR. A guide for health protection teams. October 2020. Accessed Dec 17, 2021. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/926410/Understanding_Cycle_Threshold__Ct__in_SARS-CoV-2_RT-PCR_.pdf
National Institutes of Health (NIH). Clinical Spectrum of SARS-CoV-2 Infection. Last Updated: October 19, 2021. Accessed Dec 17, 2021. Available from: https://www.covid19treatmentguidelines.nih.gov/overview/clinical-spectrum/
Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020;109:1088–95.
Madera S, Crawford E, Langelier C, et al. Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults. Sci Rep. 2021.
Paul LA, Daneman N, Schwartz KL, et al. Association of age and pediatric household transmission of SARS-CoV-2 infection. JAMA Pediatr. 2021;175:1151–58.
Funding
Funding; None
Author information
Authors and Affiliations
Contributions
Contributors: DD,MT,NS: conception and design of the work, acquisition and interpretation of data, drafting the manuscript; ML, IE: acquisition and interpretation of data for the work, revising it critically for important intellectual content. All authors approved the final version of the manuscript, and, agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Corresponding author
Ethics declarations
Ethics clearance: Institutional ethics committee, ‘P. and A. Kyriakou’ Children’s Hospital, Athens, Greece; No.4336, dated 9 March, 2021.
Competing interests; None stated.
Rights and permissions
About this article
Cite this article
Dimopoulou, D., Liaska, M., Eleftheriou, I. et al. Favorable Outcome in Infants Hospitalized With COVID-19: Single Center Experience from Athens, Greece. Indian Pediatr 59, 722–723 (2022). https://doi.org/10.1007/s13312-022-2604-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13312-022-2604-4