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Comparison of Continuous Real Time Blood Glucose Measurement With Venous Laboratory Blood Glucose Level in Neonates During Perioperative Period

Indian Pediatrics volume 59, pages 620–622 (2022)Cite this article

Abstract

Objective

To compare the continuous real time blood glucose (CG) measurement with venous laboratory blood glucose (LG) level in neonates during perioperative period.

Methods

Glucose levels were measured simultaneously by CG, glucometer glucose (GG) and LG at 40 time points in ten neonates during perioperative period. Intraclass correlation coefficient (ICC) and Bland Altman analysis were used for comparison.

Result

Correlation between CG and LG was excellent (ICC= 0.953; P<0.001), and average difference was 23.8 (95% CI 52.9 to −5.3) mg/dL, showed better reliability than at hyperglycemic state (ICC=0.653; P=0.006). The GG-LG showed excellent reliability with ICC = 0.985; P<0.001 and average difference of 15.4 (95% CI 30.7 to 0.1) mg/dL. CG at euglycemic state (ICC= 0.880; P<0.001).

Conclusion

CG measurement is reliable for blood sugar estimation in neonates; but has lower reliability for hyperglycemia. The continuous trend of glucose measurement by CG is helpful for timely diagnosis of hyperglycemia during perioperative period in neonates.

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Funding

Funding: None; Competing interests: None stated.

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Authors and Affiliations

  1. Department of Pediatrics, KIMS Hospital, Bhubaneswar, Odisha, 751 024, India

    Mohammed Abdul Wasiq, Sushree Smita Behura, Swaranjika Sahoo &  Santosh Kumar Panda

Authors
  1. Mohammed Abdul Wasiq
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  2. Sushree Smita Behura
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  3. Swaranjika Sahoo
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  4. Santosh Kumar Panda
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Contributions

Contributors: SKP: conceptualization, critical inputs to manuscript writing and supervision. MAW: principal investigator, data collection and writing manuscript. SSB: analysis and vital inputs to manuscript writing. SS: data collection and manuscript writing. All authors approved the final version of manuscript, and are accountable for all aspects related to the study.

Corresponding author

Correspondence to Santosh Kumar Panda.

Ethics declarations

Ethics clearance: IEC, KIMS; No. KIMS/KIIT/IEC/799/2022 dated Jan 13, 2022.

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Wasiq, M.A., Behura, S.S., Sahoo, S. et al. Comparison of Continuous Real Time Blood Glucose Measurement With Venous Laboratory Blood Glucose Level in Neonates During Perioperative Period. Indian Pediatr 59, 620–622 (2022). https://doi.org/10.1007/s13312-022-2575-5

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  • DOI: https://doi.org/10.1007/s13312-022-2575-5

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